Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver.
about
New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse modelsPRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient miceLysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid TurnoverSterol O-Acyltransferase 2-Driven Cholesterol Esterification Opposes Liver X Receptor-Stimulated Fecal Neutral Sterol Loss.The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters.Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse.
P2860
Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver.
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Deletion of sterol O-acyltrans ...... the small intestine and liver.
@ast
Deletion of sterol O-acyltrans ...... the small intestine and liver.
@en
type
label
Deletion of sterol O-acyltrans ...... the small intestine and liver.
@ast
Deletion of sterol O-acyltrans ...... the small intestine and liver.
@en
prefLabel
Deletion of sterol O-acyltrans ...... the small intestine and liver.
@ast
Deletion of sterol O-acyltrans ...... the small intestine and liver.
@en
P2093
P2860
P1476
Deletion of sterol O-acyltrans ...... the small intestine and liver.
@en
P2093
Adam M Lopez
Kenneth S Posey
Stephen D Turley
P2860
P304
P356
10.1016/J.BBRC.2014.10.063
P407
P577
2014-10-18T00:00:00Z