Global gene disruption in human cells to assign genes to phenotypes by deep sequencing. - sprookjes - yvandenbroek - TriplyDB

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

http://www.wikidata.org/entity/Q35036768

about

How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion Ebola virus entry requires the cholesterol transporter Niemann-Pick C1 Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)A Journey of Cytolethal Distending Toxins through Cell Membranes Making Bunyaviruses Talk: Interrogation Tactics to Identify Host Factors Required for Infection Molecular Mechanisms and Potential Clinical Applications of Campylobacter jejuni Cytolethal Distending Toxin Genome wide functional genetics in haploid cells The adherens junctions control susceptibility to Staphylococcus aureus α-toxin A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.Hunting Viral Receptors Using Haploid Cells The BioGRID interaction database: 2015 update Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death Exposure of phosphatidylserine on the cell surface Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases A CRISPR toolbox to study virus-host interactions Identification of host cell factors required for intoxication through use of modified cholera toxin Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin.A role for glycolipid biosynthesis in severe fever with thrombocytopenia syndrome virus entry.Functional toxicology: tools to advance the future of toxicity testing.The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility.Dissecting mammalian immunity through mutation.Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.CRISPR/Cas9: From Genome Engineering to Cancer Drug Discovery The cytolethal distending toxin effects on Mammalian cells: a DNA damage perspective.A conditional system to specifically link disruption of protein-coding function with reporter expression in mice Gene regulation by the act of long non-coding RNA transcription GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furin Haploid genomes illustrate epigenetic constraints and gene dosage effects in mammals.Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells.Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line.Genetic Dissection of the Host Tropism of Human-Tropic Pathogens.Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.Uptake and processing of the cytolethal distending toxin by mammalian cells.A reporter screen in a human haploid cell line identifies CYLD as a constitutive inhibitor of NF-κB.Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.Design and analysis of Bar-seq experiments.The major cellular sterol regulatory pathway is required for Andes virus infection Knocking out the door to tunicamycin entry.

P2860

Q24273350-ADC5EDAF-DDD5-4FE7-851C-5BB71B449650 Q24329246-75C66D3E-D2C5-4E98-B369-6C92C87FA875 Q24635365-3C250EF8-E658-4BBB-A77B-3133BC142AB0 Q26738908-1B45093F-9C46-40B3-9B36-C1EB940E7B02 Q26748980-96C4CE8F-3388-4DEB-847F-84A183D73882 Q26767241-8EB09934-1157-4A93-B276-B515DF940BEA Q27015889-C505DD62-137E-4AE3-8F25-A498C4F5E215 Q27321037-E7E11696-0C10-4F1A-9602-2A4631C92B88 Q27323300-54EC244C-27A7-418C-841A-3506920D5BC1 Q28080327-A53E2CDC-BD60-481C-BD01-54AE4487F243 Q28252221-EA37D920-6242-4505-B32F-3EC58F0B1C18 Q28261885-E6EC4FDE-6823-45C0-82E6-500ED7F9D044 Q28386869-EAA4ACB0-7D02-4AEC-9312-322DA18E60A4 Q28535346-F5C3614E-788D-45F6-A9A9-57A895639C1B Q29994612-0048ACC3-7659-4A47-BAE5-5861B1BCAB1A Q30467347-20C4E7C1-35FC-4A93-A5A0-DD88E8C45DF8 Q33112690-530D09FA-CB15-49BB-96F6-4CB5157F7F03 Q33292303-4075E7D7-6AEB-470F-956A-1514C0FF2875 Q33440784-E2D83963-CB90-4F16-972E-1DC156F0666F Q33595247-CC286BA2-B71D-438E-A23D-14F90288AD34 Q33628932-C20C6228-33FC-4151-AAF6-A800931033DA Q33684326-11A0F3BC-855E-48DA-9BAC-91DD78856508 Q33696265-B2353E58-9572-4D6F-9924-FD6538F5C637 Q33772342-6E5965E4-788A-4B2E-90EA-943A9127DBCC Q33883868-91415CC8-9D5C-4045-A5AD-5BC0A15F4AD5 Q33959694-89E15DE8-46D2-4042-82EC-C8C8C338338F Q34036993-D1A50992-70AA-4E93-89A2-887472857E93 Q34107128-0AB0ED82-E02F-4F6D-95F8-18416C141E5B Q34245929-DEEF0C47-AF85-45F2-9B11-BC4711F7BEB0 Q34321600-E25D115B-198B-406A-881E-5F45F00A241F Q34446440-0CC2A5E8-81C2-4AF2-8114-A0A729944C33 Q34495762-E7305A96-F059-4626-B5FE-2EC459F71CF9 Q34500340-B9932ABD-BF82-440D-85D5-67C55318BFD6 Q34581520-06F90D9C-FACC-4D97-A55D-63DBE53A6A34 Q34585020-330B6988-E361-4105-9120-D2F5AD92454B Q34828781-FB2F8228-544D-4798-9732-652CEFE5218C Q35031738-B874DA4D-2D0D-4B10-B51C-818C49EB80D8 Q35032030-D6882423-C41D-4522-BCC2-146BEC6588B6 Q35091225-560AF442-CBA3-4650-8DB1-C6B592ACA4CB Q35122989-BF0BC176-7000-4518-85A4-E9295D0642B9

P2860

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

http://www.wikidata.org/entity/Q35036768

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

@ast

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

@en

type

label

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

@ast

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

@en

prefLabel

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

@ast

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

@en

P1433

Q35036768-8E55919C-1AA3-4143-BB92-77E9144376C9

P1476

Q35036768-408CE473-A30E-4B27-AA81-55B5F65677A2

P2093

Q35036768-1BC24148-0788-4CB9-9A7A-8BC1EF4BA1E1

Q35036768-31F93055-E274-4610-A54F-57273952500D

Q35036768-32714A4F-8D4B-4C9B-81FE-27C1D6102987

Q35036768-4C6C0210-4F55-49CE-83EA-32C90DF12F30

Q35036768-5F5F2D3C-5349-439F-8506-0CA893880433

Q35036768-72E8E7B2-7286-4951-B8B5-7DE3F336C96E

Q35036768-77195FF5-0859-4287-87B3-85A31C942F8F

Q35036768-7A361E32-DD02-451D-A7BC-75D3004D31ED

Q35036768-BE312ABC-5F92-4008-8E45-1911106A351D

Q35036768-CEDE0299-D2E3-422F-9123-35608DE9EF27

P2860

Q35036768-02C54693-493E-43EC-9A01-3FB62C70D188

Q35036768-05D495DC-6EB6-49C6-B047-B7770F582924

Q35036768-0D091911-4107-4FE1-BC01-4FE736774D0E

Q35036768-1B62B824-5423-4DE1-AF9B-E528BFED3BF2

Q35036768-219EA6B4-2114-4A5B-8D15-507DA3D01BDE

Q35036768-2F2BFE62-FFC6-4B31-947E-CC1404957BD8

Q35036768-3018BF98-3256-485F-9DC8-1E31BB698868

Q35036768-3E1745D1-577A-4C16-8F0E-E82A6CCD8273

Q35036768-3F7DFFC3-4DEB-4220-ABC1-ED0DE69D555A

Q35036768-44B50EF5-AFC1-4129-ADD1-2F2FDD1557D3

P2888

Q35036768-392FA4E3-DEF5-48A2-B454-E049EDA5AB7B

P304

Q35036768-B5612FA7-16F7-4DF5-B8F8-363CBF8D1B1E

P31

Q35036768-173A8C7E-528E-4BC2-A82E-EF623E0283BB

P356

Q35036768-F4AC104C-D551-451A-AEAA-95824CB757BD

P433

Q35036768-380D7B00-3C61-420A-8C53-5B4E1844C123

P478

Q35036768-997A4747-328C-499E-845D-1F6B2B7CAF4A

P50

Q35036768-85442D2A-FD19-47D9-B9C2-5C1A1196D1B4

P577

Q35036768-D13EE41C-020E-411B-8595-2B38F00FC579

P5875

Q35036768-179CBC19-B2D8-4EC5-A7C5-3A94450CF21A

P6179

Q35036768-D9AF0794-9E35-48C7-9561-280BBEF26CBE

P698

Q35036768-97BAC02A-AEEE-4605-8FDF-F59D5B210EA4

P932

Q35036768-397EA405-2AC5-46A5-97C9-ABF8F6C1FEDD

P356

P1433

Nature Biotechnology

P1476

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

@en

P2093

Bingbing Yuan

http://www.w3.org/2001/XMLSchema#string

Carla P Guimaraes

http://www.w3.org/2001/XMLSchema#string

Chong Sun

http://www.w3.org/2001/XMLSchema#string

Hidde L Ploegh

http://www.w3.org/2001/XMLSchema#string

Irene Wuethrich

http://www.w3.org/2001/XMLSchema#string

Jan E Carette

http://www.w3.org/2001/XMLSchema#string

Malini Varadarajan

http://www.w3.org/2001/XMLSchema#string

Markus K Muellner

http://www.w3.org/2001/XMLSchema#string

Sebastian M Nijman

http://www.w3.org/2001/XMLSchema#string

Thijn R Brummelkamp

http://www.w3.org/2001/XMLSchema#string

P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Germline mutations in TMEM127 confer susceptibility to pheochromocytoma

Haploid genetic screens in human cells identify host factors used by pathogens

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

p24 and p23, the major transmembrane proteins of COPI-coated transport vesicles, form hetero-oligomeric complexes and cycle between the organelles of the early secretory pathway

Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44

BEDTools: a flexible suite of utilities for comparing genomic features.

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

The UCSC Genome Browser database: update 2010

Cellugyrin, a novel ubiquitous form of synaptogyrin that is phosphorylated by pp60c-src.

P2888

P304

542-546

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NBT.1857

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

29

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-05-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51175500

http://www.w3.org/2001/XMLSchema#string

P6179

1040790799

http://www.w3.org/2001/XMLSchema#string

P698

21623355

http://www.w3.org/2001/XMLSchema#string

P932

3111863

http://www.w3.org/2001/XMLSchema#string