Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
about
Epigenetic modulation as a therapeutic approach for pulmonary arterial hypertensionApelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular systemTargeting the Wnt signaling pathways in pulmonary arterial hypertensionApelin-APJ signaling: a potential therapeutic target for pulmonary arterial hypertensionThe emerging role of epigenetics in pulmonary arterial hypertension: an important avenue for clinical trials (2015 Grover Conference Series)Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial HypertensionA brief overview of mouse models of pulmonary arterial hypertension: problems and prospects.Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.Therapeutic implications of microRNAs in pulmonary arterial hypertension.An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertensionThe myriad essential roles of microRNAs in cardiovascular homeostasis and disease.Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonistDisruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survivalMicroRNAs in pulmonary arterial hypertension.Apelin and pulmonary hypertension.Genetic differences and aberrant methylation in the apelin system predict the risk of high-altitude pulmonary edema.Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling.Mechanisms of dysfunction in senescent pulmonary endothelium.Role of reactive oxygen and nitrogen species in the vascular responses to inflammation.Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.Identification of Biomarkers for Schistosoma-Associated Pulmonary Arterial Hypertension Based on RNA-Seq Data of Mouse Whole Lung Tissues.Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells--brief report.In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target SlugThe Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice.FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular developmentMicroRNAs in pulmonary arterial remodelingBiased G Protein-Coupled Receptor Signaling: New Player in Modulating Physiology and PathologyEndothelium as a gatekeeper of fatty acid transport.[Pyr1]Apelin-13(1-12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13.Anticipated classes of new medications and molecular targets for pulmonary arterial hypertensionMolecular biology of atherosclerosis.Lungs at high-altitude: genomic insights into hypoxic responses.Agonist-induced internalization and desensitization of the apelin receptor.Modulation of Endothelial Bone Morphogenetic Protein Receptor Type 2 Activity by Vascular Endothelial Growth Factor Receptor 3 in Pulmonary Arterial Hypertension.Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension.Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin.Discovery of a murine model of clinical PAH: Mission impossible?Advances in treatment of pulmonary arterial hypertension: patent review.
P2860
Q26801345-4B094436-0681-4B85-8C32-934AF90E717FQ26823618-10001D65-246C-483A-8360-944B069458A6Q27006826-D9A59778-B7F7-4570-9775-567E708B57A6Q27010531-FBC42A09-AF45-43C2-B762-2E6C510E41E7Q28069443-FFEAB9AA-97BE-4BAF-8079-93442B368F5DQ30032666-18899E7E-CDDE-4619-A5BD-D38AA5D4D248Q30544892-B6F751F5-585E-42F0-B0DD-99CD8B134F14Q33703037-AED959AB-88C9-45EB-A51F-71240756C9B8Q34179986-17F9F67C-E04F-4682-9AE4-DA057ADB31BAQ34319305-1066F143-016C-47B8-A726-B156F10F0966Q34356918-5FB2B0E5-C912-4B44-862E-DAA02C647AC8Q34945488-D28ABE90-CA4A-49B0-867A-659274DDE3A4Q35161744-ACC654FB-F376-4091-A79A-8D2D5B303D03Q35187029-76EB54A5-C8C0-45A9-A743-3524D2ED70A8Q35207669-FACEA447-DFD4-482E-8997-B65775433704Q35573931-7CA6DC1A-EC9C-40DA-A1F9-4F761A356C28Q35616324-18305878-2C59-4B3D-88E7-4DFFB5310D8CQ35766693-803761EA-F47F-4E7F-8D24-F09ADBDC62DFQ35815760-A072FD25-78AB-48C9-9D11-B107C44AA756Q35948515-BFC6DD18-B735-4373-9506-7E5F7CCFCBF6Q36110556-D7F9EE55-8016-4618-ACEB-EBF28802FD84Q36341659-484C73DE-3B3A-49F4-8A3B-C7535312E15DQ36389929-683BFD9E-23EE-4996-BB43-0C31F351DE8DQ36869381-2BF70A11-53AA-4E0C-BB8C-5003C008FEBFQ36878827-198ABE08-CA96-489C-A653-99AF4C47B585Q37052894-BFC01741-F4D3-4BD9-8734-ECB73F3DC858Q37084945-651D3D14-0FCD-4ADE-A6E1-2DD129E90BBBQ37308092-36A86669-A118-464C-980E-9009CE28CBBEQ37551908-73BE999F-ACA6-4295-8582-70E1014582CCQ37624930-58A89CBA-92E8-4056-8F5F-313EE840CBE0Q37670483-BDEB8D80-23D7-406A-9ABA-52ABC1D9D434Q38105550-70EDCDF3-719A-4AC9-9A49-B0DF0BC877AFQ38125279-ED08A848-F908-497F-9539-A49B1F7EE8B6Q38441794-8C6094B3-5D6D-4047-A3AF-9EA2F804DD01Q38753740-4B09BE4E-4458-4B0E-8FD4-75BA7FC3B712Q38868346-A0F645FF-7172-474F-AF6C-4B22A59BDDE8Q38893522-5FF6C443-A160-4FCD-9059-4FC0EBE40CD4Q38938652-DB2B671C-96CA-44B8-93E8-752C42F3AE5AQ39089351-474B7BBC-DDA1-42EE-B431-D38FA89A4E52Q39206788-75AA6DF5-8926-4569-A02D-8BB682D1F482
P2860
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
@ast
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
@en
type
label
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
@ast
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
@en
prefLabel
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
@ast
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
@en
P2093
P2860
P1476
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension
@en
P2093
Hedi Razavi
Hyung J Chun
Jongmin Kim
Ramendra K Kundu
Rani Agrawal
Roham T Zamanian
Suparna M Chandra
Vinicio de Jesus Perez
P2860
P304
P356
10.1161/ATVBAHA.110.219980
P407
P577
2011-01-13T00:00:00Z