Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chains
about
Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains.Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.Structure and energetic basis of overrepresented λ light chain in systemic light chain amyloidosis patients.Stabilizing an amyloidogenic λ6 light chain variable domain.Single amino acid substitution in LC-CDR1 induces Russell body phenotype that attenuates cellular protein synthesis through eIF2α phosphorylation and thereby downregulates IgG secretion despite operational secretory pathway traffic.
P2860
Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chains
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Site-directed mutagenesis reve ...... tion of human λ3r light chains
@ast
Site-directed mutagenesis reve ...... tion of human λ3r light chains
@en
type
label
Site-directed mutagenesis reve ...... tion of human λ3r light chains
@ast
Site-directed mutagenesis reve ...... tion of human λ3r light chains
@en
prefLabel
Site-directed mutagenesis reve ...... tion of human λ3r light chains
@ast
Site-directed mutagenesis reve ...... tion of human λ3r light chains
@en
P2093
P2860
P50
P356
P1476
Site-directed mutagenesis reve ...... tion of human λ3r light chains
@en
P2093
Baltazar Becerril
Daniel A Fernández-Velasco
Miryam I Villalba
Oscar D Luna-Martínez
Rosalba Sánchez-Alcalá
Sonia Rojas
Timoteo Olamendi-Portugal
P2860
P304
P356
10.1074/JBC.M114.629550
P407
P577
2014-12-11T00:00:00Z