Characterization of a common precursor to corticotropin and beta-lipotropin: cell-free synthesis of the precursor and identification of corticotropin peptides in the molecule.
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Structural organization of human genomic DNA encoding the pro-opiomelanocortin peptideSaccharomyces cerevisiae contains two discrete genes coding for the alpha-factor pheromone.Immunological evidence for two common precursors to corticotropins, endorphins, and melanotropin in the neurointermediate lobe of the toad pituitary.Concomitant synthesis of beta-endorphin and alpha-melanotropin from two forms of pro-opiomelanocortin in the rat pars intermedia.Analyzing the cryptome: uncovering secret sequences.Characterization of a common precursor to corticotropin and beta-lipotropin: identification of beta-lipotropin peptides and their arrangement relative to corticotropin in the precursor synthesized in a cell-free system.A DNA polymorphism in close physical linkage with the proopiomelanocortin gene.Secretory granules of an anterior pituitary cell line, AtT-20, contain only mature forms of corticotropin and beta-lipotropinComplete amino acid sequence of a human pituitary glycopeptide: an important maturation product of pro-opiomelanocortinImmunological identification of a common precursor to arginine vasopressin and neurophysin II synthesized by in vitro translation of bovine hypothalamic mRNA.Complete structure of the porcine pro-opiomelanocortin mRNA derived from the nucleotide sequence of cloned cDNA.Multiple cellular forms of corticotrophs in surgically removed pituitary adenomas and periadenomatous tissue in Cushing's disease.Biosynthesis of beta-endorphin from beta-lipotropin and a larger molecular weight precursor in rat pars intermediaCoordinate control of corticotropin, beta-lipotropin, and beta-endorphin release in mouse pituitary cell cultures.A subclass of proteins and sulfated macromolecules secreted by AtT-20 (mouse pituitary tumor) cells is sorted with adrenocorticotropin into dense secretory granulesPartial characterization of the mRNA that codes for enkephalins in bovine adrenal medulla and human pheochromocytoma.Adrenocortical response to corticotropin is potentiated by part of the amino-terminal region of pro-corticotropin/endorphin.Processing of the precursor to corticotropin and beta-lipotropin in humansThe Jeremiah Metzger Lecture. From POMC to functional diversity of neural peptides: the key importance of convertases.Glucocorticoid and mineralocorticoid effects on adrenocorticotropin and beta-endorphin in the adrenalectomized rat.Mineralocorticoid and glucocorticoid effects on 31,000- and 29,000-dalton proopiomelanocortin in rat anterior pituitary and neurointermediate lobe.Thyrotropin-releasing hormone stimulation of adrenocorticotropin production by mouse pituitary tumor cells in culture: possible model for anomalous release of adrenocorticotropin by thyrotropin-releasing hormone in some patients with Cushing's diseaPurification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropinCorticotropin and beta-endorphin: construction and analysis of recombinant DNA complementary to mRNA for the common precursor.Immunological and chemical identification of a neurophysin-containing protein coded by messenger RNA from bovine hypothalamus.beta-Lipotropin is the major opioid-like peptide of human pituitary and rat pars distalis: lack of significant beta-endorphinConstruction of bacterial plasmids that contain the nucleotide sequence for bovine corticotropin-beta-lipotropin precursor.Pituitary somatotrophs contain [Met]enkephalin-like immunoreactivity.Isolation of pancreatic trypsin inhibitor from bovine pituitary glands.In vitro synthesis of thymosin beta 4 encoded by rat spleen mRNAAction potentials and membrane ion channels in clonal anterior pituitary cellsMonoclonal antibody to the message sequence Tyr-Gly-Gly-Phe of opioid peptides exhibits the specificity requirements of mammalian opioid receptors.Beta-endorphin and beta-lipotropin secretion by an ACTH-secreting mouse pituitary tumor.The role of glycosylation on the biosynthesis, degradation, and secretion of the ACTH-beta-lipotropin common precursor and its peptide products.Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors.Distribution of beta-endorphin-related peptides in rat pituitary and brain.Signaling mechanisms controlled by melanocortins in melanoma, lacrimal, and brain astroglial cells.Expression of the human proenkephalin gene in mouse pituitary cells: accurate and efficient mRNA production and proteolytic processingPresence of a pre-sequence (signal sequence) in the common precursor to ACTH and endorphin and the role of glycosylation in processing of the precursor and secretion of ACTH and endorphin.Targeting and processing of pro-opiomelanocortin in neuronal cell lines.
P2860
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P2860
Characterization of a common precursor to corticotropin and beta-lipotropin: cell-free synthesis of the precursor and identification of corticotropin peptides in the molecule.
description
1977 nî lūn-bûn
@nan
1977 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1977 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
name
Characterization of a common p ...... opin peptides in the molecule.
@ast
Characterization of a common p ...... opin peptides in the molecule.
@en
type
label
Characterization of a common p ...... opin peptides in the molecule.
@ast
Characterization of a common p ...... opin peptides in the molecule.
@en
prefLabel
Characterization of a common p ...... opin peptides in the molecule.
@ast
Characterization of a common p ...... opin peptides in the molecule.
@en
P2860
P356
P1476
Characterization of a common p ...... opin peptides in the molecule.
@en
P2093
P2860
P304
P356
10.1073/PNAS.74.11.4826
P407
P577
1977-11-01T00:00:00Z