The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.
about
The demoiselle of X-inactivation: 50 years old and as trendy and mesmerising as everX Chromosome of female cells shows dynamic changes in status during human somatic cell reprogramming.A prominent and conserved role for YY1 in Xist transcriptional activation.Coupling of X-chromosome reactivation with the pluripotent stem cell state.The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression.Xist regulation and function explored.Evolutionary diversity and developmental regulation of X-chromosome inactivation.Pluripotency factor binding and Tsix expression act synergistically to repress Xist in undifferentiated embryonic stem cells.The lesser known story of X chromosome reactivation: a closer look into the reprogramming of the inactive X chromosome.Solving the "X" in embryos and stem cellsNew and Xisting regulatory mechanisms of X chromosome inactivationReleasing the break on X chromosome inactivation: Rnf12/RLIM targets REX1 for degradation.Overexpression of OCT4A ortholog elevates endogenous XIST in porcine parthenogenic blastocysts.Dynamic interplay and function of multiple noncoding genes governing X chromosome inactivation.Epigenetics of pluripotent cells.Cis- and trans-regulation in X inactivation.The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo.Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization.X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells.Xist and Tsix Transcription Dynamics Is Regulated by the X-to-Autosome Ratio and Semistable Transcriptional States.Establishment of X chromosome inactivation and epigenomic features of the inactive X depend on cellular contexts.OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males.RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation.
P2860
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P2860
The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
The X-inactivation trans-activ ...... ctors in embryonic stem cells.
@ast
The X-inactivation trans-activ ...... ctors in embryonic stem cells.
@en
type
label
The X-inactivation trans-activ ...... ctors in embryonic stem cells.
@ast
The X-inactivation trans-activ ...... ctors in embryonic stem cells.
@en
prefLabel
The X-inactivation trans-activ ...... ctors in embryonic stem cells.
@ast
The X-inactivation trans-activ ...... ctors in embryonic stem cells.
@en
P2860
P1433
P1476
The X-inactivation trans-activ ...... actors in embryonic stem cells
@en
P2093
Michael Moffat
Pablo Navarro
P2860
P2888
P304
P356
10.1007/S00439-011-0998-5
P577
2011-05-05T00:00:00Z