The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
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The dual role of tumor lymphatic vessels in dissemination of metastases and immune response developmentChemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinomaCCR7 mediates human breast cancer cell invasion, migration by inducing epithelial-mesenchymal transition and suppressing apoptosis through AKT pathway.Tumor hypoxia modulates podoplanin/CCL21 interactions in CCR7+ NK cell recruitment and CCR7+ tumor cell mobilization.CCL21/CCR7 interaction promotes cellular migration and invasion via modulation of the MEK/ERK1/2 signaling pathway and correlates with lymphatic metastatic spread and poor prognosis in urinary bladder cancer.G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis.miR-199a-5p suppresses human bladder cancer cell metastasis by targeting CCR7.PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cells.CCL21-CCR7 promotes the lymph node metastasis of esophageal squamous cell carcinoma by up-regulating MUC1.Silencing of CCR7 inhibits the growth, invasion and migration of prostate cancer cells induced by VEGFCExpression of CCL21 in Ewing sarcoma shows an inverse correlation with metastases and is a candidate target for immunotherapy.Peri-articular lymphatic system and "Bi" theory of Chinese medicine in the pathogenesis and treatment of arthritis.CCL5 promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-507 in human chondrosarcoma cells.Role of tumor microenvironment in tumorigenesis.Construction of specific magnetic resonance imaging/optical dual-modality molecular probe used for imaging angiogenesis of gastric cancer.Stromal contributions to the carcinogenic process.CCR7 promote lymph node metastasis via regulating VEGF-C/D-R3 pathway in lung adenocarcinoma.ELM: A New, Simple, and Economic Assay to Measure Motility of Lymphatic Endothelial Cells.CCR7 Maintains Nonresolving Lymph Node and Adipose Inflammation in Obesity.Chemokines in homeostasis and diseases.Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges.Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors.Chemokine CCL4 Induces Vascular Endothelial Growth Factor C Expression and Lymphangiogenesis by miR-195-3p in Oral Squamous Cell Carcinoma.CCR7 regulates ANO6 to promote migration of pancreatic ductal adenocarcinoma cells via the ERK signaling pathway.Alterations of Signaling Pathways Related to the Immune System in Breast Cancer: New Perspectives in Patient ManagementHypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
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P2860
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
description
2015 nî lūn-bûn
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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
name
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
@ast
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
@en
type
label
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
@ast
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
@en
prefLabel
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
@ast
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
@en
P2093
P2860
P1433
P1476
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
@en
P2093
Elena Tutunea-Fatan
Mousumi Majumder
Peeyush K Lala
Xiping Xin
P2860
P2888
P356
10.1186/S12943-015-0306-4
P577
2015-02-10T00:00:00Z
P5875
P6179
1035617051