A vaccine strategy that induces protective immunity against heroin.
about
Future pharmacological treatments for substance use disordersPharmacokinetic correlates of the effects of a heroin vaccine on heroin self-administration in ratsChronic CRF1 receptor blockade reduces heroin intake escalation and dependence-induced hyperalgesiaVaccines against drugs of abuse: where are we now?Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphineLiposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs.Novel pharmacotherapeutic strategies for treatment of opioid-induced neonatal abstinence syndrome.Synthesis and immunological effects of heroin vaccinesCan you vaccinate against substance abuse?Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines.Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats.A conjugate vaccine attenuates morphine- and heroin-induced behavior in ratsAnti-addiction vaccines.Adjuvants for vaccines to drugs of abuse and addiction.Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriersPharmacokinetic strategies for treatment of drug overdose and addiction.An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia.Developing a vaccine against multiple psychoactive targets: a case study of heroin.Vaccines against drug abuse.Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats.The unrealized potential of addiction science in curbing the HIV epidemicInvestigating the effects of a hydrolytically stable hapten and a Th1 adjuvant on heroin vaccine performance.A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuseEnhancing nicotine vaccine immunogenicity with liposomes.Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in ratsAnti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice.Combatting Synthetic Designer Opioids: A Conjugate Vaccine Ablates Lethal Doses of Fentanyl Class DrugsDynamic vaccine blocks relapse to compulsive intake of heroin.A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats.Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacyRecent advances in the molecular design of synthetic vaccines.Conjugate Vaccine Immunotherapy for Substance Use Disorder.Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alumBiologics to treat substance use disorders: Current status and new directionsStructurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities.Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens.Current status and future prospects for the development of substance abuse vaccines.Development of a Clinically Viable Heroin Vaccine.A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse.Current challenges for the creation of effective vaccines against drugs of abuse.
P2860
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P2860
A vaccine strategy that induces protective immunity against heroin.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A vaccine strategy that induces protective immunity against heroin.
@ast
A vaccine strategy that induces protective immunity against heroin.
@en
type
label
A vaccine strategy that induces protective immunity against heroin.
@ast
A vaccine strategy that induces protective immunity against heroin.
@en
prefLabel
A vaccine strategy that induces protective immunity against heroin.
@ast
A vaccine strategy that induces protective immunity against heroin.
@en
P2093
P2860
P356
P1476
A vaccine strategy that induces protective immunity against heroin.
@en
P2093
Alexander V Mayorov
G Neil Stowe
George F Koob
Gery Schulteis
Joel E Schlosburg
Joseph S Zakhari
Kaushik K Misra
Kim D Janda
Leandro F Vendruscolo
Scott Edwards
P2860
P304
P356
10.1021/JM200461M
P407
P577
2011-06-30T00:00:00Z