IQGAPs choreograph cellular signaling from the membrane to the nucleus
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Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and DiseaseCdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1The IQD Family of Calmodulin-Binding Proteins Links Calcium Signaling to Microtubules, Membrane Subdomains, and the Nucleus.Compartmentalization of membrane trafficking, glucose transport, glycolysis, actin, tubulin and the proteasome in the cytoplasmic droplet/Hermes body of epididymal sperm.Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration.Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancerIQGAP1: insights into the function of a molecular puppeteer.IQGAP1 is a phosphoinositide effector and kinase scaffoldAbsence of IQGAP1 Protein Leads to Insulin Resistance.Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.Exploring the genetics of feed efficiency and feeding behaviour traits in a pig line highly selected for performance characteristics.Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression.Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α.Annexin A6 - a multifunctional scaffold in cell motility.IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity.IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-κB pathway.BcIqg1, a fungal IQGAP homolog, interacts with NADPH oxidase, MAP kinase and calcium signaling proteins and regulates virulence and development in Botrytis cinerea.The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.ERK Signals: Scaffolding Scaffolds?The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2.Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.Ras GAP-related and C-terminal domain-dependent localization and tumorigenic activities of IQGAP1 in melanoma cells.Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2.The Scaffolding Protein IQGAP1 Interacts with NLRC3 and Inhibits Type I IFN Production.New model for the interaction of IQGAP1 with CDC42 and RAC1.And Akt-ion! IQGAP1 in control of signaling pathways.Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42.Downregulation of IQGAP2 Correlates with Prostate Cancer Recurrence and Metastasis
P2860
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P2860
IQGAPs choreograph cellular signaling from the membrane to the nucleus
description
2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
IQGAPs choreograph cellular signaling from the membrane to the nucleus
@ast
IQGAPs choreograph cellular signaling from the membrane to the nucleus
@en
type
label
IQGAPs choreograph cellular signaling from the membrane to the nucleus
@ast
IQGAPs choreograph cellular signaling from the membrane to the nucleus
@en
prefLabel
IQGAPs choreograph cellular signaling from the membrane to the nucleus
@ast
IQGAPs choreograph cellular signaling from the membrane to the nucleus
@en
P2860
P1476
IQGAPs choreograph cellular signaling from the membrane to the nucleus
@en
P2093
Andrew C Hedman
Jessica M Smith
P2860
P304
P356
10.1016/J.TCB.2014.12.005
P577
2015-01-21T00:00:00Z