Targeting Rb inactivation in cancers by synthetic lethality.
about
Collateral Lethality: A new therapeutic strategy in oncologyHyperactivated Wnt signaling induces synthetic lethal interaction with Rb inactivation by elevating TORC1 activities.Down-regulation of SOSTDC1 promotes thyroid cancer cell proliferation via regulating cyclin A2 and cyclin E2ESCRT-0 complex modulates Rbf-mutant cell survival by regulating Rhomboid endosomal trafficking and EGFR signalingConserved RB functions in development and tumor suppression.Regulation of cell polarity determinants by the Retinoblastoma tumor suppressor protein.Functional inactivation of Rb sensitizes cancer cells to TSC2 inactivation induced cell deathMutation of the retinoblastoma tumor suppressor gene sensitizes cancers to mitotic inhibitor induced cell death.
P2860
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P2860
Targeting Rb inactivation in cancers by synthetic lethality.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Targeting Rb inactivation in cancers by synthetic lethality.
@ast
Targeting Rb inactivation in cancers by synthetic lethality.
@en
type
label
Targeting Rb inactivation in cancers by synthetic lethality.
@ast
Targeting Rb inactivation in cancers by synthetic lethality.
@en
prefLabel
Targeting Rb inactivation in cancers by synthetic lethality.
@ast
Targeting Rb inactivation in cancers by synthetic lethality.
@en
P2860
P1476
Targeting Rb inactivation in cancers by synthetic lethality
@en
P2093
Gabriel M Gordon
P2860
P304
P577
2011-06-01T00:00:00Z