Genes that modify the hemochromatosis phenotype in mice. - sprookjes - yvandenbroek - TriplyDB

Genes that modify the hemochromatosis phenotype in mice.

Genes that modify the hemochromatosis phenotype in mice.

http://www.wikidata.org/entity/Q35159180

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DMT1, a physiologically relevant apical Cu1+ transporter of intestinal cells A mouse model of juvenile hemochromatosis.Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis Recent advances in understanding haemochromatosis: a transition state Genetic predisposition to iron overload: prevalence and phenotypic expression of hemochromatosis-associated HFE-C282Y gene mutation Mechanisms of divalent metal toxicity in affective disorders Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice Pathophysiological consequences and benefits of HFE mutations: 20 years of research.Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis The ins and outs of bacterial iron metabolism.Pumping iron: the strange partnership of the hemochromatosis protein, a class I MHC homolog, with the transferrin receptor.The many faces of host responses to tuberculosis.Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis Physiology of iron transport and the hemochromatosis gene.Haemochromatosis: understanding the mechanism of disease and implications for diagnosis and patient management following the recent cloning of novel genes involved in iron metabolism.Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation.Variable phenotypic presentation of iron overload in H63D homozygotes: are genetic modifiers the cause?The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading.Underdiagnosis of hereditary haemochromatosis: lack of presentation or penetration?SLC11A1 promoter gene polymorphisms and fibrosis progression in chronic hepatitis C.Expression of E-cadherin and other paracellular junction genes is decreased in iron-loaded hepatocytes Iron loading and morbidity among relatives of HFE C282Y homozygotes identified either by population genetic testing or presenting as patients.Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta 2-microglobulin-deficient mice.Diet, genetics, and disease: a focus on the middle East and north Africa region.Effect of olfactory manganese exposure on anxiety-related behavior in a mouse model of iron overload hemochromatosis.Impact of epidermal desquamation on tissue stores of iron.HFE gene mutations in susceptibility to childhood leukemia: HuGE review.The molecular genetics of haemochromatosis.Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations.Iron in skin of mice with three etiologies of systemic iron overload.The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.CYBRD1 as a modifier gene that modulates iron phenotype in HFE p.C282Y homozygous patients.Forging a field: the golden age of iron biology.Iron overload and immunity.

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P2860

Genes that modify the hemochromatosis phenotype in mice.

http://www.wikidata.org/entity/Q35159180

description

2000 nî lūn-bûn

@nan

2000 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի մայիսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

@zh-hk

2000年論文

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2000年論文

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2000年论文

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name

Genes that modify the hemochromatosis phenotype in mice.

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Genes that modify the hemochromatosis phenotype in mice.

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Genes that modify the hemochromatosis phenotype in mice.

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Genes that modify the hemochromatosis phenotype in mice.

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prefLabel

Genes that modify the hemochromatosis phenotype in mice.

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Genes that modify the hemochromatosis phenotype in mice.

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Journal of Clinical Investigation

P1476

Genes that modify the hemochromatosis phenotype in mice.

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P2093

J E Levy

http://www.w3.org/2001/XMLSchema#string

L K Montross

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N C Andrews

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P2860

Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

Juvenile hemochromatosis locus maps to chromosome 1q.

Transferrin receptor is necessary for development of erythrocytes and the nervous system

Experimental hemochromatosis due to MHC class I HFE deficiency: immune status and iron metabolism

The C282Y mutation causing hereditary hemochromatosis does not produce a null allele

Disorders of iron metabolism

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

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1209-1216

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10.1172/JCI9635

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9

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10791995

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315447

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