Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. - sprookjes - yvandenbroek - TriplyDB

Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

http://www.wikidata.org/entity/Q35168294

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The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity Stem cells in genetically-engineered mouse models of prostate cancer Insights into Chemoresistance of Prostate Cancer Neuroendocrine differentiation in prostate cancer: a mechanism of radioresistance and treatment failure In vitro human cell line models to predict clinical response to anticancer drugs Translating insights of AR signaling from mouse models Targeting the adaptive molecular landscape of castration-resistant prostate cancer Genetically engineered mouse models of prostate cancer Posttranslational regulation of Akt in human cancer Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and PH domain and leucine-rich repeat phosphatase cross-talk (PHLPP) in cancer cells and in transforming growth factor β-activated stem cells Concurrent Down-Regulation of PTEN and NKX3.1 Expression in Iranian Patients with Prostate Cancer Suppression of survival signalling pathways by the phosphatase PHLPP N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer Transcriptional activity of c-Jun is critical for the suppression of AR function.MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.Targeted androgen pathway suppression in localized prostate cancer: a pilot study.VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway.Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.The role of GATA2 in lethal prostate cancer aggressiveness.Molecular pathology of prostate cancer revealed by next-generation sequencing: opportunities for genome-based personalized therapy.Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer Mouse models of prostate cancer: picking the best model for the question.Elevated YKL40 is associated with advanced prostate cancer (PCa) and positively regulates invasion and migration of PCa cells PIP5K1α inhibition as a therapeutic strategy for prostate cancer The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.Determining PTEN functional status by network component deduced transcription factor activities The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer Synergistic simvastatin and metformin combination chemotherapy for osseous metastatic castration-resistant prostate cancer.Androgen receptor antagonists in castration-resistant prostate cancer.Targeting the androgen receptor in the management of castration-resistant prostate cancer: rationale, progress, and future directions Molecular pathways and targets in prostate cancer Identification of CD166 as a surface marker for enriching prostate stem/progenitor and cancer initiating cells Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model PTEN genomic deletion predicts prostate cancer recurrence and is associated with low AR expression and transcriptional activity.Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling.Concomitant loss of EAF2/U19 and Pten synergistically promotes prostate carcinogenesis in the mouse model.

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P2860

Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

http://www.wikidata.org/entity/Q35168294

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2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

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Ashkan Morim

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David J Mulholland

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Hong Wu

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Houjian Cai

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Isla P Garraway

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Jiaoti Huang

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Linh M Tran

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Seema Plaisier

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Shunyou Wang

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Yunfeng Li

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P2860

ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms

An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

The program of androgen-responsive genes in neoplastic prostate epithelium.

Identification of a cell of origin for human prostate cancer

Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study

Development of a second-generation antiandrogen for treatment of advanced prostate cancer

Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP

PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells

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