Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation.
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Huntingtin Is Required for Neural But Not Cardiac/Pancreatic Progenitor Differentiation of Mouse Embryonic Stem Cells In vitro.Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy.Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels.The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's DiseaseHuntington's Disease as Neurodevelopmental Disorder: Altered Chromatin Regulation, Coding, and Non-Coding RNA Transcription.A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.Contribution of Neuroepigenetics to Huntington's Disease.Altered enhancer transcription underlies Huntington's disease striatal transcriptional signatureHuntington Disease as a Neurodevelopmental Disorder and Early Signs of the Disease in Stem Cells.Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.Epigenetics of Huntington's Disease.Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity.Role of non-coding RNAs in non-aging-related neurological disorders.
P2860
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P2860
Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Htt CAG repeat expansion confe ...... ction in chromatin regulation.
@ast
Htt CAG repeat expansion confe ...... ction in chromatin regulation.
@en
type
label
Htt CAG repeat expansion confe ...... ction in chromatin regulation.
@ast
Htt CAG repeat expansion confe ...... ction in chromatin regulation.
@en
prefLabel
Htt CAG repeat expansion confe ...... ction in chromatin regulation.
@ast
Htt CAG repeat expansion confe ...... ction in chromatin regulation.
@en
P2093
P2860
P50
P356
P1476
Htt CAG repeat expansion confe ...... ction in chromatin regulation.
@en
P2093
Ashok Ragavendran
Fatih Ozsolak
Ihn Sik Seong
Jong Min Lee
Marcy E Macdonald
Nicole Solomos
Peter J Park
Poornima Manavalan
Ravi Vijayvargia
Yijing Zhang
P2860
P304
P356
10.1093/HMG/DDV006
P50
P577
2015-01-08T00:00:00Z