Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429. - sprookjes - yvandenbroek - TriplyDB

Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429.

Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429.

http://www.wikidata.org/entity/Q35332004

about

The pharmacology of neurokinin receptors in addiction: prospects for therapy Role of cues and contexts on drug-seeking behaviour Animal models of alcohol and drug dependence Gut-brain peptides in corticostriatal-limbic circuitry and alcohol use disorders Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress.Convergent pharmacological mechanisms in impulsivity and addiction: insights from rodent models.Pharmacological stress is required for the anti-alcohol effect of the α3β4* nAChR partial agonist AT-1001 Translational and reverse translational research on the role of stress in drug craving and relapse.The neurokinin-1 receptor antagonist aprepitant in co-morbid alcohol dependence and posttraumatic stress disorder: a human experimental study.Laboratory-induced stress and craving among individuals with prescription opioid dependence.Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking.Stress-related neuropeptides and addictive behaviors: beyond the usual suspects.Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in Wistar rats.The NK1 receptor antagonist L822429 reduces heroin reinforcement.Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training.Emerging targets for addiction neuropharmacology: From mechanisms to therapeutics The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking Investigational therapies for the pharmacological treatment of alcoholism.Molecular basis of alcoholism.Postdependent state in rats as a model for medication development in alcoholism.The Role of NFkB in Drug Addiction: Beyond Inflammation.The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description.Neurobiology of comorbid post-traumatic stress disorder and alcohol-use disorder.Posttraumatic Stress Disorder and Alcohol Use Disorder: A Critical Review of Pharmacologic Treatments.Pharmacokinetics and central nervous system effects of the novel dual NK1 /NK3 receptor antagonist GSK1144814 in alcohol-intoxicated volunteers.TACR1 genotypes predict fMRI response to alcohol cues and level of alcohol dependence.Placebo- and amitriptyline-controlled evaluation of central nervous system effects of the NK1 receptor antagonist aprepitant and intravenous alcohol infusion at pseudo-steady state.Cluster and meta-analyses on factors influencing stress-induced alcohol drinking and relapse in rodents.Bidirectional relationship between alcohol intake and sensitivity to social defeat: association with Tacr1 and Avp expression.The Corticotropin Releasing Factor Receptor 1 in Alcohol Use Disorder: Still a Valid Drug Target?Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models.Substance P in the anterior thalamic paraventricular nucleus: promotion of ethanol drinking in response to orexin from the hypothalamus.Anti-stress neuropharmacological mechanisms and targets for addiction treatment: A translational framework

P2860

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P2860

Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429.

http://www.wikidata.org/entity/Q35332004

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Stress-induced reinstatement o ...... in 1 (NK1) antagonist L822429.

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Stress-induced reinstatement o ...... in 1 (NK1) antagonist L822429.

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Jesse R Schank

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Kejun Cheng

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Kelly E Rowe

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Kenner C Rice

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Yavin Shaham

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P2860

The neurokinin 1 receptor antagonist, ezlopitant, reduces appetitive responding for sucrose and ethanol

Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence

Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation

Neurokinin 1 receptor antagonism as a possible therapy for alcoholism

Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence.

Differential effects of the CRF-R1 antagonist GSK876008 on fear-potentiated, light- and CRF-enhanced startle suggest preferential involvement in sustained vs phasic threat responses.

Corticotropin-releasing factor-1 receptor activation mediates nicotine withdrawal-induced deficit in brain reward function and stress-induced relapse

The role of substance P in stress and anxiety responses.

Incubation of conditioned fear in the conditioned suppression model in rats: role of food-restriction conditions, length of conditioned stimulus, and generality to conditioned freezing.

Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function.

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10.1007/S00213-011-2201-Z

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218

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Annika Thorsell

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49854516

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21340476

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