Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function
about
Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repairEmerging roles of the nucleolus in regulating the DNA damage response: the noncanonical DNA repair enzyme APE1/Ref-1 as a paradigmatical exampleMitochondrial DNA damage induced autophagy, cell death, and diseaseNucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cellsIdentification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor.APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsSpecific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell linesThe redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate.Mitochondrial translocation of APE1 relies on the MIA pathway.Nuclear depletion of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) is an indicator of energy disruption in neuronsSuppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease.Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Proteome-wide discovery of mislocated proteins in cancerRegulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.The anti-inflammatory role of extranuclear apurinic/apyrimidinic endonuclease 1/redox effector factor-1 in reactive astrocytes.Human apurinic/apyrimidinic endonuclease 1.Mitochondrial protein translocases for survival and wellbeing.Mechanisms Regulating Protein Localization.Human mitochondrial nucleases.Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.Protein-disulfide isomerase regulates the thyroid hormone receptor-mediated gene expression via redox factor-1 through thiol reduction-oxidation.Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression.Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin.Effect of estrogens on base excision repair in brain and liver mitochondria of aged female rats.
P2860
Q26822957-14C87B78-ABAD-445A-A531-B4124DE77232Q27026649-0617E2B2-00E5-4300-8B2F-4297BFD8D79FQ28072518-2CBFDB62-8E81-4A45-8E26-15DC8FE7F8EAQ30420636-D6EE4FA1-20F6-4D5E-93B7-CBFE8844F1BDQ33632423-99D368DC-A47D-4607-9EBA-29D21166E220Q33990581-26FF4486-9BF6-4050-B8A6-9C6EFA5B2CC0Q34963206-B16F8C93-9AD2-4EB7-86B2-D8CCA1E25B3DQ35106907-93522B11-9EA7-4372-91BA-D0CD66EA9F02Q35770659-F4F2DC85-ACB2-4861-A2C8-6F4D439586A6Q36367362-5D4A25D4-C616-4E42-AD29-8462017622D2Q36837710-E0BBC860-F9C7-4FC8-B793-CE31C9D0F451Q36996445-AAF45C2E-0A41-4B02-8BAB-70B9CC970ED8Q37061173-480A560E-C23A-4C33-B4C3-2120F7405C23Q37225608-351F6B62-50BE-4C12-BC54-4D9745685209Q37510883-CB8C9FAF-3CB7-46C2-9B56-CD28CF566DC0Q37512952-249FC20A-E5DE-4315-915E-4304AA2F6335Q38215345-7BB0F495-4B0D-446D-98EA-1DDEB647201BQ38546818-BE811C42-7EA7-4661-8220-F6B1DEA94A14Q39031724-957F5B4A-15E3-4A80-800C-F4FEDB813C77Q39129437-031D0694-3682-4857-9685-29AF49016975Q39245533-573F5220-ECFF-4C4D-8633-D9C6E7C8CB61Q41999364-A39DC28E-ACD7-4CDB-AAB3-691739FFDC36Q42127225-2E1C2E66-15D2-4828-80D7-3AAE732FB837Q44740203-3389F7AB-EB0C-473F-98E6-B245DF71D91CQ49425463-645F3BE4-AE42-4042-A24A-CC17AE5D1408Q51243999-91735113-BAD1-49DC-80B9-367D603A89BE
P2860
Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Knock-in reconstitution studie ...... lular trafficking and function
@ast
Knock-in reconstitution studie ...... lular trafficking and function
@en
type
label
Knock-in reconstitution studie ...... lular trafficking and function
@ast
Knock-in reconstitution studie ...... lular trafficking and function
@en
prefLabel
Knock-in reconstitution studie ...... lular trafficking and function
@ast
Knock-in reconstitution studie ...... lular trafficking and function
@en
P2093
P2860
P356
P1476
Knock-in reconstitution studie ...... lular trafficking and function
@en
P2093
Andrea Scaloni
Carlo Vascotto
Chiara D'Ambrosio
Elena Bisetto
Fabio Altieri
Franco Quadrifoglio
Irene Mavelli
Leo A H Zeef
Marina Comelli
Mark R Kelley
P2860
P304
P356
10.1091/MBC.E11-05-0391
P577
2011-08-24T00:00:00Z