Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF. - sprookjes - yvandenbroek - TriplyDB

Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

http://www.wikidata.org/entity/Q35470449

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Pathways and therapeutic targets in melanoma An Integrative Analysis of Preeclampsia Based on the Construction of an Extended Composite Network Featuring Protein-Protein Physical Interactions and Transcriptional Relationships REST is a hypoxia-responsive transcriptional repressor HIF1α and HIF2α independently activate SRC to promote melanoma metastases Molecular pathways: BRAF induces bioenergetic adaptation by attenuating oxidative phosphorylation.Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma A novel hypoxia-associated subset of FN1 high MITF low melanoma cells: identification, characterization, and prognostic value.MITF in melanoma: mechanisms behind its expression and activity.Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin.MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.Hypoxia and PGE(2) regulate MiTF-CX during cervical ripening Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts.Prostaglandin E2 regulates its own inactivating enzyme, 15-PGDH, by EP2 receptor-mediated cervical cell-specific mechanisms.Acid sphingomyelinase determines melanoma progression and metastatic behaviour via the microphtalmia-associated transcription factor signalling pathway.Putative role of HIF transcriptional activity in melanocytes and melanoma biology.The roles of microphthalmia-associated transcription factor and pigmentation in melanoma.Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy.Microphthalmia-associated transcription factor expression levels in melanoma cells contribute to cell invasion and proliferation.RNA SEQ Analysis Indicates that the AE3 Cl-/HCO3- Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart.Somatic driver mutations in melanoma.Hypoxia and MITF regulate KIT oncogenic properties in melanocytes.Acidic tumor microenvironment in human melanoma.Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.Glucose availability controls ATF4-mediated MITF suppression to drive melanoma cell growth.Clinical significance of hypoxia-inducible factor 1 and VEGF-A in osteosarcoma.HIF-1 is involved in the negative regulation of AURKA expression in breast cancer cell lines under hypoxic conditions.Targeting invasive properties of melanoma cells.The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology.Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications.Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions.Phenotypic diversity of patient-derived melanoma populations in stem cell medium.Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway.Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance.Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms.

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

http://www.wikidata.org/entity/Q35470449

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

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type

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

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PNAS.1106351108

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Proceedings of the National Academy of Sciences of the United States of America

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF

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P2093

Carmit Levy

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David E Fisher

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Erez Feige

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Mehdi Khaled

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Scott R Granter

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Stephen Lee

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Vivien Igras

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P2860

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

A conserved family of prolyl-4-hydroxylases that modify HIF

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer

Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomas

Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation

MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

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E924-33

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10.1073/PNAS.1106351108

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43

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108

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Hans R. Widlund

Satoru Yokoyama

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2011-09-26T00:00:00Z

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51665399

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