Differential clinicopathologic and genetic features of late-onset amnestic dementias - sprookjes - yvandenbroek - TriplyDB

Differential clinicopathologic and genetic features of late-onset amnestic dementias

Differential clinicopathologic and genetic features of late-onset amnestic dementias

http://www.wikidata.org/entity/Q35545502

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Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation Hippocampal Sclerosis of Aging Can Be Segmental: Two Cases and Review of the Literature Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A Chronic traumatic encephalopathy pathology in a neurodegenerative disorders brain bank.Primary age-related tauopathy (PART): a common pathology associated with human aging Prevalence of mixed pathologies in the aging brain Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology The TMEM106B locus and TDP-43 pathology in older persons without FTLD TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features.ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target.Brain pathologies in extreme old age.Cerebellar ataxia in progressive supranuclear palsy: An autopsy study of PSP-C.Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe.Challenges of multimorbidity of the aging brain: a critical update.Case Studies Illustrating Focal Alzheimer's, Fluent Aphasia, Late-Onset Memory Loss, and Rapid Dementia.Overcoming translational barriers impeding development of Alzheimer's disease modifying therapies.Hippocampal Sclerosis in Older Patients: Practical Examples and Guidance With a Focus on Cerebral Age-Related TDP-43 With Sclerosis."New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).What we know about TMEM106B in neurodegeneration.CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2.Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.LRRK2 variation and dementia with Lewy bodies.The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases.18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study.Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations.Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons.Hippocampal sclerosis, hippocampal neuron loss patterns and Tdp-43 in the aged population.Parkinson's disease susceptibility variants and severity of Lewy body pathology.Distribution and characteristics of transactive response DNA binding protein 43 kDa pathology in progressive supranuclear palsy.Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice.MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies.Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration.Characterization of brain anatomical patterns by comparing region intensity distributions: Applications to the description of Alzheimer's disease.Hippocampal Sclerosis in the Oldest Old: A Finnish Population-Based Study.Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.TMEM106B haplotypes have distinct gene expression patterns in aged brain.

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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Acta Neuropathologica

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Differential clinicopathologic and genetic features of late-onset amnestic dementias

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Amanda M Liesinger

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Ashley Cannon

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Minerva M Carrasquillo

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Neill R Graff-Radford

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Nicola J Rutherford

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Ranjan Duara

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Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

Neuropathological stageing of Alzheimer-related changes

Focal cortical presentations of Alzheimer's disease

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.

Common variant in GRN is a genetic risk factor for hippocampal sclerosis in the elderly.

Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons.

Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathy.

TDP-43 is a key player in the clinical features associated with Alzheimer's disease

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study.

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s00401-014-1302-2

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411-421

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scholarly article

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10.1007/S00401-014-1302-2

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3

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128

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Rosa Rademakers

Dennis W. Dickson

Melissa E. Murray

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2014-06-05T00:00:00Z

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262927263

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24899141

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4412022

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