Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
about
Pharmacological treatment options for mast cell activation diseaseAspirin-exacerbated respiratory disease: pathophysiological insights and clinical advancesLipid mediators and allergic diseasesPGE suppresses excessive anti-IgE induced cysteinyl leucotrienes production in mast cells of patients with aspirin exacerbated respiratory diseaseProstaglandin E2 prevents hyperosmolar-induced human mast cell activation through prostanoid receptors EP2 and EP4.Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity.Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator releaseDistinct PGE2-responder and non-responder phenotypes in human mast cell populations: "all or nothing" enhancement of antigen-dependent mediator release.Regulation of mast cell responses in health and disease.Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation PathwayG protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation.E-prostanoid 2 receptors dampen mast cell degranulation via cAMP/PKA-mediated suppression of IgE-dependent signaling.Differential release of mast cell mediators and the pathogenesis of inflammation.Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release.Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienes.Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impactActivity of the cyclooxygenase 2-prostaglandin-E prostanoid receptor pathway in mice exposed to house dust mite aeroallergens, and impact of exogenous prostaglandin E2.Prostaglandin E2 mediates cough via the EP3 receptor: implications for future disease therapy.Protease-activated receptors and prostaglandins in inflammatory lung disease.Mast cell phenotype, TNFα expression and degranulation status in non-small cell lung cancerRole of PGE2 in asthma and nonasthmatic eosinophilic bronchitis.Novel biomarkers for asthma stratification and personalized therapy.Cyclooxygenase 2: its regulation, role and impact in airway inflammation.Current complications and treatment of aspirin-exacerbated respiratory disease.Are Mast Cells MASTers in Cancer?Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migrationMast cell chemotaxis - chemoattractants and signaling pathways.Characterization of the EP receptor subtype that mediates the inhibitory effects of prostaglandin E2 on IgE-dependent secretion from human lung mast cells.Bone marrow stromal cells inhibit mast cell function via a COX2-dependent mechanismFrontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology.Prostaglandin E2 suppresses human group 2 innate lymphoid cell function.Activation of the Prostaglandin E2 receptor EP2 prevents house dust mite-induced airway hyperresponsiveness and inflammation by restraining mast cells' activity.The occurrence of refractoriness and mast cell mediator release following mannitol-induced bronchoconstriction.Editorial: Yin-Yang of EP receptor expression.Eicosanoid Control Over Antigen Presenting Cells in Asthma
P2860
Q26748784-6DC24AD9-257D-4C4C-B670-C5BD74908936Q26750424-9893718F-F875-4DF6-9C9D-A6989F379D2AQ27023936-8903F9B8-3BBE-4ECD-A179-1AC29A93AB26Q28210926-A9606F4B-ABF8-40DB-8A43-BFFCC55EBCCFQ34374532-2EBC0123-F789-4E3F-AB3C-780FCF187F4CQ34434995-F6E93A3F-4264-47A8-BD7D-AD604E95D3E0Q34452585-35A91EA2-2ABF-417D-AC7D-7E9F42E66578Q35491013-C7318A7D-E4E4-4CA5-BF4F-ABB2D05EFD65Q36092456-32F12FBA-903D-411B-B0F1-FA9B2832461AQ36119388-E301FF2F-23C0-4E8D-8D15-3A9FEF743909Q36168847-1C4363C1-7614-43B2-B1D3-CA442432C5A7Q36410794-A0174D56-737C-402D-8844-5CDC51EF3224Q36819882-4C3886D6-846F-4117-8716-4B5ACF4B3EC4Q37215940-A7B55D03-41A5-459E-916E-90B7C194153CQ37240446-CD00CB44-756B-4CD8-84CC-44E3A6ED38EAQ37348262-0F048503-5C33-4C08-970A-74A1E82D9713Q37418337-36F0CE31-8E84-40EA-A60A-B580CEF495ACQ37423141-1CE88DC5-E453-4097-9D20-AEF808D344AFQ37447476-A5605499-D998-40F9-8EC4-4D94EBE76E3BQ37475819-F8251E24-1E1F-4E1B-A44E-5D3A33D3BF69Q38005107-956E00AF-8991-455F-851D-92C095A951E2Q38283811-69C6DC32-D039-4764-920E-5B72141849E2Q38674101-C3FA6ABF-C43E-40E1-A27E-51B3EF5617AFQ39000200-FC5D5BCD-A81C-48EE-8391-AAF6E18D8C48Q39265436-54E261E6-777A-44ED-AF73-F888034E58DFQ41306787-EB644C61-9165-4E9A-8B62-6A1592F718B6Q42177446-E55CC787-C68F-49D7-AABF-95E54FAEF537Q42710611-5CFC7E2E-AD42-48AC-BE46-6CB12BDFE6F9Q42717964-1638F5A7-7B53-452A-B8B7-FFA4D7A0FFC1Q44873639-5B233DA2-D5B2-44CB-AF79-0D66CF76157FQ50025252-C4C47E23-9F7D-4525-8951-A915EBF807B0Q50449176-FA1C6F1C-B4C0-4635-A308-FA77BD6684B0Q53273655-42643120-D7B5-49E0-8E27-B937265E50C4Q54468195-460694D0-49D3-450F-9A8C-378793C59AD0Q58764843-AFA1D821-7ED9-40CA-A076-888669C4F8CA
P2860
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
@ast
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
@en
type
label
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
@ast
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
@en
prefLabel
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
@ast
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
@en
P2860
P356
P1476
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation
@en
P2093
Linda J Kay
Peter T Peachell
P2860
P304
P356
10.1038/SJ.BJP.0706664
P407
P577
2006-04-01T00:00:00Z