Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition - sprookjes - yvandenbroek - TriplyDB

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

http://www.wikidata.org/entity/Q35634476

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Cancer pharmacogenomics: strategies and challenges Different interaction profiles of direct-acting anti-hepatitis C virus agents with human organic anion transporting polypeptides Acute lymphoblastic leukaemia Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics Plasma membrane transporters in modern liver pharmacology A health-care system perspective on implementing genomic medicine: pediatric acute lymphoblastic leukemia as a paradigm Pharmacogenomics discovery and implementation in genome-wide association studies era Pharmacogenomics of chemotherapeutic susceptibility and toxicity Pharmacogenomics in Pediatric Oncology: Review of Gene-Drug Associations for Clinical Use Pharmacogenetics predictive of response and toxicity in acute lymphoblastic leukemia therapy Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset.Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma.State of Art of Cancer Pharmacogenomics in Latin American Populations.Polymorphisms in methotrexate transporters and their relationship to plasma methotrexate levels, toxicity of high-dose methotrexate, and outcome of pediatric acute lymphoblastic leukemia.Haplotype kernel association test as a powerful method to identify chromosomal regions harboring uncommon causal variants.Clinical implementation of germ line cancer pharmacogenetic variants during the next-generation sequencing era.Expression of mRNA transcripts encoding membrane transporters detected with whole transcriptome sequencing of human brain and liver Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance.A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required.The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update.The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.Pharmacogenomics and individualized medicine: translating science into practice.Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy.SLCO1B1 and SLC19A1 gene variants and irinotecan-induced rapid response and survival: a prospective multicenter pharmacogenetics study of metastatic colorectal cancer The physiological role of drug transporters.Inherited genetic variation in childhood acute lymphoblastic leukemia.Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?Pharmacogenomics of adverse effects of anti-leukemic agents in children.Relating human genetic variation to variation in drug responses.Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel.OATP1B1 polymorphism as a determinant of erythromycin disposition.SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization.Genome-wide study of methotrexate clearance replicates SLCO1B1.Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide Inherited variation in OATP1B1 is associated with treatment outcome in acute myeloid leukemia.Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1 PGRNseq: a targeted capture sequencing panel for pharmacogenetic research and implementation.Involvement of Multiple Transporters-mediated Transports in Mizoribine and Methotrexate Pharmacokinetics.

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Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

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Gary L Rosner

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Lisa R Treviño

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Predicting deleterious amino acid substitutions

A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase

Inference of population structure using multilocus genotype data

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

Treating childhood acute lymphoblastic leukemia without cranial irradiation

A New Statistical Method for Haplotype Reconstruction from Population Data

A method and server for predicting damaging missense mutations

A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

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10.1101/GR.129668.111

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1

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Thomas Juhl Corydon

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51858082

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22147369

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