Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors
about
Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy.Tumor Microenvironment as a New Target for Tumor Immunotherapy of Polysaccharides.Adenoviral Delivery of Tumor Necrosis Factor-α and Interleukin-2 Enables Successful Adoptive Cell Therapy of Immunosuppressive Melanoma.Adenoviral production of interleukin-2 at the tumor site removes the need for systemic postconditioning in adoptive cell therapy.Syngeneic syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting.IL-2 mediates NK cell proliferation but not hyperactivity.Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses.Co-transfer of tumor-specific effector and memory CD8+ T cells enhances the efficacy of adoptive melanoma immunotherapy in a mouse model.
P2860
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P2860
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Favorable alteration of tumor ...... T-cell therapy in solid tumors
@ast
Favorable alteration of tumor ...... T-cell therapy in solid tumors
@en
type
label
Favorable alteration of tumor ...... T-cell therapy in solid tumors
@ast
Favorable alteration of tumor ...... T-cell therapy in solid tumors
@en
prefLabel
Favorable alteration of tumor ...... T-cell therapy in solid tumors
@ast
Favorable alteration of tumor ...... T-cell therapy in solid tumors
@en
P2093
P2860
P50
P1433
P1476
Favorable alteration of tumor ...... T-cell therapy in solid tumors
@en
P2093
Saija Kaikkonen
Siri Tähtinen
Suvi Parviainen
P2860
P304
P356
10.1371/JOURNAL.PONE.0131242
P407
P50
P577
2015-06-24T00:00:00Z