Targeting protein-protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies?

Targeting protein-protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies?

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http://www.wikidata.org/entity/Q35687836
Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL)Enhancements to the Rosetta Energy Function Enable Improved Identification of Small Molecules that Inhibit Protein-Protein InteractionsChiPPI: a novel method for mapping chimeric protein-protein interactions uncovers selection principles of protein fusion events in cancer.When cancer and immunology meetRational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand ComplexesDARC: Mapping Surface Topography by Ray-Casting for Effective Virtual Screening at Protein Interaction Sites.Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in CancerA Pyrazolo[3,4-d]pyrimidine Compound Reduces Cell Viability and Induces Apoptosis in Different Hematological Malignancies.Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation.Theoretical models of inhibitory activity for inhibitors of protein–protein interactions: targeting menin–mixed lineage leukemia with small molecules† †Electronic Supplementary Information (ESI) available: Detailed characterization of the compound cTheoretical models of inhibitory activity for inhibitors of protein-protein interactions: targeting menin-mixed lineage leukemia with small molecules.
P2860

Targeting protein-protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies?

Item
http://www.wikidata.org/entity/Q35687836
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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Targeting protein-protein inte ...... ortunity for future therapies?
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Targeting protein-protein inte ...... ortunity for future therapies?
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Targeting protein-protein inte ...... ortunity for future therapies?
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Targeting protein-protein inte ...... ortunity for future therapies?
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Targeting protein-protein inte ...... ortunity for future therapies?
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Targeting protein-protein inte ...... ortunity for future therapies?
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Targeting protein-protein inte ...... ortunity for future therapies?
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P2093
P2860
P304
P31
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P433
P478
P577
P698
P932