Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli.
about
Engineered external guide sequences are highly effective in inducing RNase P for inhibition of gene expression and replication of human cytomegalovirusThe smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirusRNase P Ribozymes Inhibit the Replication of Human Cytomegalovirus by Targeting Essential Viral Capsid ProteinsDissecting human cytomegalovirus gene function and capsid maturation by ribozyme targeting and electron cryomicroscopyEngineered RNase P ribozymes effectively inhibit human cytomegalovirus gene expression and replicationSalmonella-mediated delivery of RNase P-based ribozymes for inhibition of viral gene expression and replication in human cells.Yeast two hybrid analyses reveal novel binary interactions between human cytomegalovirus-encoded virion proteins.Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase PRNase P-mediated inhibition of cytomegalovirus protease expression and viral DNA encapsidation by oligonucleotide external guide sequences.Effective inhibition of herpes simplex virus 1 gene expression and growth by engineered RNase P ribozyme.A novel ribozyme-based prophylaxis inhibits influenza A virus replication and protects from severe disease.Intracellular expression of engineered RNase P ribozymes effectively blocks gene expression and replication of human cytomegalovirusEngineered external guide sequences effectively block viral gene expression and replication in cultured cells.RNase P: variations and uses.A Hsp40 chaperone protein interacts with and modulates the cellular distribution of the primase protein of human cytomegalovirus.Effective inhibition of human immunodeficiency virus 1 replication by engineered RNase P ribozyme.Oral delivery of RNase P ribozymes by Salmonella inhibits viral infection in mice.Infection of human cytomegalovirus in cultured human gingival tissue.Human cytomegalovirus primase UL70 specifically interacts with cellular factor Snapin.RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions.Characterization of the expression of Salmonella Type III secretion system factor PrgI, SipA, SipB, SopE2, SpaO, and SptP in cultures and in mice.Modulation of the cellular distribution of human cytomegalovirus helicase by cellular factor Snapin.In vitro selection of external guide sequences for directing RNase P-mediated inhibition of viral gene expression.RNase P-Mediated Sequence-Specific Cleavage of RNA by Engineered External Guide SequencesRibonuclease P-mediated inhibition of human cytomegalovirus gene expression and replication induced by engineered external guide sequences.RNase P ribozyme inhibits cytomegalovirus replication by blocking the expression of viral capsid proteins.Effective inhibition of human cytomegalovirus gene expression and growth by intracellular expression of external guide sequence RNA.Engineered RNase P ribozymes increase their cleavage activities and efficacies in inhibiting viral gene expression in cells by enhancing the rate of cleavage and binding of the target mRNA.Engineered RNase P ribozymes are efficient in cleaving a human cytomegalovirus mRNA in vitro and are effective in inhibiting viral gene expression and growth in human cells.Inhibition of human cytomegalovirus immediate early gene expression and growth by a novel RNase P ribozyme variant.Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.
P2860
Q25257324-A407B8BE-5444-4A7D-B337-65B074053AE3Q28535363-8F1C4672-5D41-4816-8671-1E4604A89A1FQ28646176-1B2A8D71-289E-4B5D-898F-7E4C9E6F0D72Q33780745-3D054D0F-B898-4599-A053-F518E15A262EQ33820722-CA799BF6-EF7E-46D8-8274-47B530EF989AQ33842038-2997E44E-4706-449C-8E8E-007C2E20AE01Q33869574-A5F697B0-AFAA-46A3-8067-648CEE321017Q33911877-2401AEEC-AA56-4A3C-84B7-C33303412B2AQ33952670-752066F6-D6AE-414B-8651-F01B01D5AAFCQ34004603-77496654-4BCC-4E91-91B7-07268EE7E02BQ34081491-0D460BEE-93E8-42F2-9FFF-0F028B40284EQ34366924-E5D1F763-B1AE-4F3B-B453-4D449EE9CC7FQ34452558-90A89814-35FF-4119-B8F0-847B83807D8AQ34462159-A1F1427B-552C-4D9B-ADD2-6C94B3ACFDA9Q34468973-7A84315A-1D8C-484A-AD10-E6A22B0E1B09Q34540271-75AD6D7C-1A9B-446D-B10C-5011AD36072EQ34602827-9648278E-3CC4-40ED-9F1E-22B0BB22EB1AQ35100976-064C54F4-73F9-4637-8A21-D706C1BEC8BEQ35531256-C128DB26-91B0-4EDB-98A5-BE939F609047Q35943427-D1961316-7B94-4EBF-BF22-AEBA3C0BA957Q37182191-E30364B5-A339-4EAB-B1C4-2A855C94D532Q37252926-13B10046-0D4A-43C0-B8F4-36D3386DE892Q38288559-3FB44390-9066-44E2-9AB2-6E926078DA42Q38633823-3998568C-E13A-438F-B8D0-D74BFD0A7D51Q39270183-E5C8AF98-D49F-46AD-8B75-81AF6F3CA82DQ40541066-B0146DEB-3157-4D9B-9C76-645098738E02Q43207494-E6BE737C-86B5-4E42-8F3C-C4D0427ACA60Q44148116-3E8867E2-17F1-4561-8172-BEB9F89F40C7Q45863741-9D7312FD-7FBC-4611-BC93-A73B8F65A21AQ46218614-9063910D-5345-4476-A39C-5C6B9FA172E0Q47548273-C53F9B58-0AD4-4265-97C2-E45E69F4569E
P2860
Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Effective inhibition of human ...... RNase P from Escherichia coli.
@ast
Effective inhibition of human ...... RNase P from Escherichia coli.
@en
type
label
Effective inhibition of human ...... RNase P from Escherichia coli.
@ast
Effective inhibition of human ...... RNase P from Escherichia coli.
@en
prefLabel
Effective inhibition of human ...... RNase P from Escherichia coli.
@ast
Effective inhibition of human ...... RNase P from Escherichia coli.
@en
P2093
P2860
P356
P1476
Effective inhibition of human ...... RNase P from Escherichia coli.
@en
P2093
P2860
P304
P356
10.1073/PNAS.100101797
P407
P577
2000-05-01T00:00:00Z