Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias.
about
Lung surfactant levels are regulated by Ig-Hepta/GPR116 by monitoring surfactant protein DThe mitochondrial heme exporter FLVCR1b mediates erythroid differentiationTBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stressIneffective erythropoiesis and thalassemiasHepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic miceOxidative stress in β-thalassaemia and sickle cell diseaseBody iron delocalization: the serious drawback in iron disorders in both developing and developed countriesIneffective erythropoiesis in β -thalassemiaTranslational control by heme-regulated eIF2α kinase during erythropoiesisOxidative stress and β-thalassemic erythroid cells behind the molecular defectModulation of hepcidin as therapy for primary and secondary iron overload disorders: preclinical models and approachesStructural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactisControls of Nuclear Factor-Kappa B Signaling Activity by 5'-AMP-Activated Protein Kinase Activation With Examples in Human Bladder Cancer CellsNovel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic MiceEnhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasisThe function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturationRespiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) phosphorylation to maintain translation and viral replicationArabidopsis eIF2alpha kinase GCN2 is essential for growth in stress conditions and is activated by woundingIron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.Impact of heme on specific antibody production in mice: promotive, inhibitive or null outcome is determined by its concentration.Uridine affects liver protein glycosylation, insulin signaling, and heme biosynthesis.Hepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2alpha kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of basal endoplasmic reticulum stress toneNitric oxide blocks cellular heme insertion into a broad range of heme proteinsNew frontiers in translational control of the cancer genomeER stress, autophagy, and RNA viruses.Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response.A critical role for mTORC1 in erythropoiesis and anemia.Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.Hemin binds to human cytoplasmic arginyl-tRNA synthetase and inhibits its catalytic activityRoles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal.Blood meal-derived heme decreases ROS levels in the midgut of Aedes aegypti and allows proliferation of intestinal microbiota.PKR-dependent CHOP induction limits hyperoxia-induced lung injury.The host-encoded Heme Regulated Inhibitor (HRI) facilitates virulence-associated activities of bacterial pathogens.Iron homeostasis and the inflammatory responseExplorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinaseAssessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing.The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis.Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells
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P2860
Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Regulation of protein synthesi ...... kinase: relevance to anemias.
@ast
Regulation of protein synthesi ...... kinase: relevance to anemias.
@en
type
label
Regulation of protein synthesi ...... kinase: relevance to anemias.
@ast
Regulation of protein synthesi ...... kinase: relevance to anemias.
@en
prefLabel
Regulation of protein synthesi ...... kinase: relevance to anemias.
@ast
Regulation of protein synthesi ...... kinase: relevance to anemias.
@en
P2860
P1433
P1476
Regulation of protein synthesi ...... kinase: relevance to anemias.
@en
P2093
Jane-Jane Chen
P2860
P304
P356
10.1182/BLOOD-2006-08-041830
P407
P577
2007-04-01T00:00:00Z