Increased reactive oxygen species production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin-resistant human skeletal muscle
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The Emerging Role of Branched-Chain Amino Acids in Insulin Resistance and MetabolismChemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the TargetSkeletal Muscle Mitochondrial Bioenergetics and Morphology in High Fat Diet Induced Obesity and Insulin Resistance: Focus on Dietary Fat SourceCalcineurin inhibition and new-onset diabetes mellitus after transplantationSources and implications of NADH/NAD(+) redox imbalance in diabetes and its complicationsBranched-chain amino acids in metabolic signalling and insulin resistanceEffect of short-term thyroxine administration on energy metabolism and mitochondrial efficiency in humansThe Janus Head of Oxidative Stress in Metabolic Diseases and During Physical Exercise.Adenine nucleotide translocase is acetylated in vivo in human muscle: Modeling predicts a decreased ADP affinity and altered control of oxidative phosphorylation.Staphylococcus aureus sepsis induces early renal mitochondrial DNA repair and mitochondrial biogenesis in mice.Mitochondrial complex I deficiency enhances skeletal myogenesis but impairs insulin signaling through SIRT1 inactivation.Skeletal muscle phosphodiester content relates to body mass and glycemic control.Effect of calcium on the oxidative phosphorylation cascade in skeletal muscle mitochondriaOverfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans.Unraveling biochemical pathways affected by mitochondrial dysfunctions using metabolomic approaches.Disrupting mitochondrial-nuclear coevolution affects OXPHOS complex I integrity and impacts human health.Effects of acute exposure to increased plasma branched-chain amino acid concentrations on insulin-mediated plasma glucose turnover in healthy young subjects.Elevated NF-κB activation is conserved in human myocytes cultured from obese type 2 diabetic patients and attenuated by AMP-activated protein kinaseMitochondrial dysfunction and insulin resistance from the outside in: extracellular matrix, the cytoskeleton, and mitochondria.Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training.Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.Pathobiochemical changes in diabetic skeletal muscle as revealed by mass-spectrometry-based proteomicsAntioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome.Mitochondrial dysfunction in insulin resistance: differential contributions of chronic insulin and saturated fatty acid exposure in muscle cellsIntrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoformDifferential Mitochondrial Adaptation in Primary Vascular Smooth Muscle Cells from a Diabetic Rat Model.Obesity-induced tissue free radical generation: an in vivo immuno-spin trapping study.ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity.The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese ratsProteomics analyses of subcutaneous adipocytes reveal novel abnormalities in human insulin resistance.The positive association of branched-chain amino acids and metabolic dyslipidemia in Chinese Han population.Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans.Mitochondrial respiratory capacity and content are normal in young insulin-resistant obese humans.Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria.Global IRS-1 phosphorylation analysis in insulin resistance.Resistance training to improve type 2 diabetes: working toward a prescription for the future.Mitochondrial pathophysiology and type 2 diabetes mellitus.The role of mitochondria in insulin resistance and type 2 diabetes mellitus.Mitochondrial reactive oxygen species and risk of atherosclerosis.Insulin resistance and the metabolism of branched-chain amino acids.
P2860
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P2860
Increased reactive oxygen species production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin-resistant human skeletal muscle
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Increased reactive oxygen spec ...... esistant human skeletal muscle
@ast
Increased reactive oxygen spec ...... esistant human skeletal muscle
@en
type
label
Increased reactive oxygen spec ...... esistant human skeletal muscle
@ast
Increased reactive oxygen spec ...... esistant human skeletal muscle
@en
prefLabel
Increased reactive oxygen spec ...... esistant human skeletal muscle
@ast
Increased reactive oxygen spec ...... esistant human skeletal muscle
@en
P2093
P2860
P356
P1433
P1476
Increased reactive oxygen spec ...... esistant human skeletal muscle
@en
P2093
Benjamin Bowen
Brian Glancy
Christian Meyer
Colleen Brophy
Elena A De Filippis
Kurt Højlund
Lawrence J Mandarino
Natalie Lefort
Wayne T Willis
Zachary Bailowitz
P2860
P304
P356
10.2337/DB10-0174
P407
P50
P577
2010-08-03T00:00:00Z