SIRT1 is dispensable for function of hematopoietic stem cells in adult mice. - sprookjes - yvandenbroek - TriplyDB

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

http://www.wikidata.org/entity/Q35802214

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Sirtuins in hematological aging and malignancy Role of SIRT1 in the growth and regulation of normal hematopoietic and leukemia stem cells Emerging Roles of SIRT1 in Cancer Drug Resistance A potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neurons Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells ARAP3 functions in hematopoietic stem cells SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.Inhibition of CD26/DPP-IV enhances donor muscle cell engraftment and stimulates sustained donor cell proliferation Connecting Mitochondria, Metabolism, and Stem Cell Fate.Enhancing engraftment of cord blood cells via insight into the biology of stem/progenitor cell function.CD150(-) Side Population Defines Leukemia Stem Cells in a BALB/c Mouse Model of CML and Is Depleted by Genetic Loss of SIRT1 Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate.Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance Sirtuins, tissue maintenance, and tumorigenesis.Roles of SIRT1 in leukemogenesis.Dietary and metabolic control of stem cell function in physiology and cancer.Role of sirtuins in stem cell differentiation.Intercellular interplay between Sirt1 signalling and cell metabolism in immune cell biology.SIRT1 activates the expression of fetal hemoglobin genes SIRT1-mediated transcriptional regulation of SOX2 is important for self-renewal of liver cancer stem cells.SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice.As"SIRT"ing the role of an epigenetic modifier in hematopoietic stem cell homeostasis.Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases.Sirtuins at the crossroads of stemness, aging, and cancer.

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P2860

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

http://www.wikidata.org/entity/Q35802214

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

@ast

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

@en

type

label

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

@ast

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

@en

prefLabel

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

@ast

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

@en

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BLOOD-2011-09-377077

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SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

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P2093

Antonio Bedalov

http://www.w3.org/2001/XMLSchema#string

Barbara Varnum-Finney

http://www.w3.org/2001/XMLSchema#string

Cynthia Nourigat

http://www.w3.org/2001/XMLSchema#string

David Flowers

http://www.w3.org/2001/XMLSchema#string

Hongzhe Li

http://www.w3.org/2001/XMLSchema#string

Irwin D Bernstein

http://www.w3.org/2001/XMLSchema#string

Vid Leko

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Yansong Gu

http://www.w3.org/2001/XMLSchema#string

P2860

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Resveratrol improves health and survival of mice on a high-calorie diet

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

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1856-1860

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scholarly article

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10.1182/BLOOD-2011-09-377077

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8

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119

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2012-01-04T00:00:00Z

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51983914

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22219225

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3293640

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