An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.
about
APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutantbeta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization.Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.Increased AβPP processing in familial Danish dementia patients.Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants.
P2860
An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
An NSAID-like compound, FT-9, ...... loid precursor-like protein 1.
@ast
An NSAID-like compound, FT-9, ...... loid precursor-like protein 1.
@en
type
label
An NSAID-like compound, FT-9, ...... loid precursor-like protein 1.
@ast
An NSAID-like compound, FT-9, ...... loid precursor-like protein 1.
@en
prefLabel
An NSAID-like compound, FT-9, ...... loid precursor-like protein 1.
@ast
An NSAID-like compound, FT-9, ...... loid precursor-like protein 1.
@en
P2093
P2860
P356
P1433
P1476
An NSAID-like compound, FT-9, ...... loid precursor-like protein 1.
@en
P2093
Abdul Fauq
Carlo Sala Frigerio
Dominic M Walsh
Paul C Engel
Thomas L Kukar
Todd E Golde
P2860
P304
10894-10904
P356
10.1021/BI901237K
P407
P577
2009-11-01T00:00:00Z