Differential effects of bryostatin 1 and 12-O-tetradecanoylphorbol-13-acetate on the regulation and activation of RasGRP1 in mouse epidermal keratinocytes.
about
RasGRPs are targets of the anti-cancer agent ingenol-3-angelateMarine pharmacology in 2005-2006: antitumour and cytotoxic compounds.Transgenic overexpression of RasGRP1 in mouse epidermis results in spontaneous tumors of the skin.RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.RasGRP1 transgenic mice develop cutaneous squamous cell carcinomas in response to skin wounding: potential role of granulocyte colony-stimulating factorTargeted deletion of RasGRP1 impairs skin tumorigenesis.RasGRP1 is essential for ras activation by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in epidermal keratinocytes.
P2860
Q28535474-2D147AA7-DDC3-4C5E-AE0B-7FE1812364DAQ33359943-9EC93CC9-4542-46D3-975F-126DBEA379D7Q35828864-11C3BE8F-2FF6-465C-8344-73ED186D8295Q37219204-B13E7B87-DC74-4089-9F8A-D382EBC5EACFQ37257218-4661C178-2A85-4149-9CF7-7EF94F364ACBQ37731516-31A490F2-8519-4620-848B-7F2092CA0DE4Q39724715-3CF60D71-1795-4CF3-9994-31BC789BE1A9
P2860
Differential effects of bryostatin 1 and 12-O-tetradecanoylphorbol-13-acetate on the regulation and activation of RasGRP1 in mouse epidermal keratinocytes.
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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name
Differential effects of bryost ...... mouse epidermal keratinocytes.
@ast
Differential effects of bryost ...... mouse epidermal keratinocytes.
@en
type
label
Differential effects of bryost ...... mouse epidermal keratinocytes.
@ast
Differential effects of bryost ...... mouse epidermal keratinocytes.
@en
prefLabel
Differential effects of bryost ...... mouse epidermal keratinocytes.
@ast
Differential effects of bryost ...... mouse epidermal keratinocytes.
@en
P2093
P2860
P1476
Differential effects of bryost ...... mouse epidermal keratinocytes.
@en
P2093
Carolyn E Oki
Matthew C Tuthill
Patricia S Lorenzo
P2860
P304
P356
10.1158/1535-7163.MCT-05-0317
P577
2006-03-01T00:00:00Z