Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.
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Conditional gene expression in the mouse inner ear using Cre-loxP.Sensory hair cell development and regeneration: similarities and differencesCanonical Notch signaling plays an instructive role in auditory supporting cell development.Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse ReformationAuditory hair cell-specific deletion of p27Kip1 in postnatal mice promotes cell-autonomous generation of new hair cells and normal hearing.Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochleaChanges in the adult vertebrate auditory sensory epithelium after trauma.Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells.Development of hair cells in inner ear is associated with expression and promoter methylation of Notch-1 in postnatal mice.Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium.Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear.Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo.Signaling mechanisms controlling cranial placode neurogenesis and delamination.Notch signaling in mammalian hair cell regeneration.Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea.Notch Signaling in Development, Tissue Homeostasis, and Disease.Shaping of inner ear sensory organs through antagonistic interactions between Notch signalling and Lmx1a.Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells.Regeneration of Cochlear Hair Cells and Hearing Recovery through Hes1 Modulation with siRNA Nanoparticles in Adult Guinea Pigs
P2860
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P2860
Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
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2012年论文
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2012年论文
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2012年论文
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name
Overactivation of Notch1 signa ...... ar in an age-dependent manner.
@ast
Overactivation of Notch1 signa ...... ar in an age-dependent manner.
@en
type
label
Overactivation of Notch1 signa ...... ar in an age-dependent manner.
@ast
Overactivation of Notch1 signa ...... ar in an age-dependent manner.
@en
prefLabel
Overactivation of Notch1 signa ...... ar in an age-dependent manner.
@ast
Overactivation of Notch1 signa ...... ar in an age-dependent manner.
@en
P2093
P2860
P1433
P1476
Overactivation of Notch1 signa ...... ar in an age-dependent manner.
@en
P2093
P2860
P304
P356
10.1371/JOURNAL.PONE.0034123
P407
P577
2012-03-20T00:00:00Z