KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.
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New drugs in prostate cancerThe brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma.Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells.Erratum to: KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin in prostate cancer models.Exportin 1 (XPO1) inhibition leads to restoration of tumor suppressor miR-145 and consequent suppression of pancreatic cancer cell proliferation and migration.Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer.A Phase II Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant Prostate Cancer.Phase II study of the oral selective inhibitor of nuclear export (SINE) KPT-335 (verdinexor) in dogs with lymphomaDown-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression
P2860
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P2860
KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
KPT-330, a potent and selectiv ...... ed] in prostate cancer models.
@ast
KPT-330, a potent and selectiv ...... ed] in prostate cancer models.
@en
type
label
KPT-330, a potent and selectiv ...... ed] in prostate cancer models.
@ast
KPT-330, a potent and selectiv ...... ed] in prostate cancer models.
@en
prefLabel
KPT-330, a potent and selectiv ...... ed] in prostate cancer models.
@ast
KPT-330, a potent and selectiv ...... ed] in prostate cancer models.
@en
P2093
P2860
P1433
P1476
KPT-330, a potent and selectiv ...... ted] in prostate cancer models
@en
P2093
Claudio Festuccia
Dilara McCauley
Flora Vitale
Giovanni Luca Gravina
Luca Ventura
Michael Kauffman
Patrizia Sanita
Sharon Shacham
Yosef Landesman
P2860
P2888
P356
10.1186/S12885-015-1936-Z
P407
P577
2015-12-01T00:00:00Z
P5875
P6179
1035114564