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Antiproliferative Fate of the Tetraploid Formed after Mitotic Slippage and Its Promotion; A Novel Target for Cancer Therapy Based on Microtubule PoisonsRoles for retrotransposon insertions in human diseasePhyllanthus emblica Fruit Extract Activates Spindle Assembly Checkpoint, Prevents Mitotic Aberrations and Genomic Instability in Human Colon Epithelial NCM460 Cells.DNA replication stress mediates APOBEC3 family mutagenesis in breast cancerA renewed model of pancreatic cancer evolution based on genomic rearrangement patternsGenomics, Endoscopy, and Control of Gastroesophageal Cancers: A Perspective.Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.Ontogeny of Unstable Chromosomes Generated by Telomere Error in Budding Yeast.Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes.Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis.Effects of Combined Treatment with Ionizing Radiation and the PARP Inhibitor Olaparib in BRCA Mutant and Wild Type Patient-Derived Pancreatic Cancer Xenografts.Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumorsThe tandem duplicator phenotype as a distinct genomic configuration in cancerRif1 Regulates the Fate of DNA Entanglements during Mitosis.Guarding chromosomes from oxidative DNA damage to the very endWhen Genome Maintenance Goes Badly Awry.A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.CTLPScanner: a web server for chromothripsis-like pattern detectionNuclear envelope rupture is induced by actin-based nucleus confinement.Nuclear envelope rupture drives genome instability in cancerIdentification of complex genomic rearrangements in cancers using CouGaRThe Consequences of Chromosome Segregation Errors in Mitosis and Meiosis.Stop pulling my strings - what telomeres taught us about the DNA damage response.Y chromothripsis?Nuclear envelope rupture is enhanced by loss of p53 or Rb.Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining.From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes.Impaired nuclear functions in micronuclei results in genome instability and chromothripsis.Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1.Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis.Molecular genetics of osteosarcoma.Telomeres in cancer: tumour suppression and genome instability.Catastrophic cellular events leading to complex chromosomal rearrangements in the germline.Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.The Role of Aneuploidy in Cancer Evolution.Chromosomal Instability as a Driver of Tumor Heterogeneity and Evolution.The nucleus: keeping it together by keeping it apart.Telomere-driven diseases and telomere-targeting therapies.Bursting the Bubble - Nuclear Envelope Rupture as a Path to Genomic Instability?Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres.
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Chromothripsis and Kataegis Induced by Telomere Crisis
@ast
Chromothripsis and Kataegis Induced by Telomere Crisis
@en
type
label
Chromothripsis and Kataegis Induced by Telomere Crisis
@ast
Chromothripsis and Kataegis Induced by Telomere Crisis
@en
prefLabel
Chromothripsis and Kataegis Induced by Telomere Crisis
@ast
Chromothripsis and Kataegis Induced by Telomere Crisis
@en
P2093
P2860
P1433
P1476
Chromothripsis and Kataegis Induced by Telomere Crisis
@en
P2093
Nazario Bosco
Peter J Campbell
P2860
P304
P356
10.1016/J.CELL.2015.11.054
P407
P577
2015-12-01T00:00:00Z