Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases. - sprookjes - yvandenbroek - TriplyDB

Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

http://www.wikidata.org/entity/Q35889638

about

Breast cancer brain metastases: the last frontier PI3K pathway inhibitors for the treatment of brain metastases with a focus on HER2+ breast cancer Breast cancer brain metastases: biology and new clinical perspectives Efficacy and safety of dose-dense chemotherapy in urothelial carcinoma.PI3K pathway activation in high-grade ductal carcinoma in situ--implications for progression to invasive breast carcinoma.Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer Identification of collaborative driver pathways in breast cancer.Activation of Akt/mTOR pathway is associated with poor prognosis of nasopharyngeal carcinoma.Relevance of PTEN loss in brain metastasis formation in breast cancer patients Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases.EGFR and HER2 signaling in breast cancer brain metastasis.Therapeutic targets in triple negative breast cancer.PI3K in cancer-stroma interactions: bad in seed and ugly in soil.Systemic therapy of brain metastases.Mystery of the brain metastatic disease in breast cancer patients: improved patient stratification, disease prediction and targeted prevention on the horizon?Metastasis as an evolutionary process.Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN ERβ1 inversely correlates with PTEN/PI3K/AKT pathway and predicts a favorable prognosis in triple-negative breast cancer.A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard.Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer.Potential Molecular Signatures Predictive of Lung Cancer Brain Metastasis.

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P2860

Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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type

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Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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Breast Cancer Research

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Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.

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Aleix Prat

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Allison M Deal

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Barbara Adamo

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C Ryan Miller

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Carey K Anders

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Chad Livasy

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Emily Burrows

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Erika Hamilton

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J Chuck Harrell

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Joseph Geradts

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P2860

Latent bone metastasis in breast cancer tied to Src-dependent survival signals

Knockin of mutant PIK3CA activates multiple oncogenic pathways

High frequency of mutations of the PIK3CA gene in human cancers

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

The biology and clinical relevance of the PTEN tumor suppressor pathway

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

Breast cancer brain metastases: differences in survival depending on biological subtype, RPA RTOG prognostic class and systemic treatment after whole-brain radiotherapy (WBRT).

Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

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10.1186/BCR3071

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