Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine.
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Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer's Disease.Hippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation.Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels(-)-Phenserine attenuates soman-induced neuropathologyCognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic MechanismsΒ-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neuronsSynthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-Synuclein synthesis, interleukin-1β release, and cholNeural Stem Cell Transplant-Induced Effect on Neurogenesis and Cognition in Alzheimer Tg2576 Mice Is Inhibited by Concomitant Treatment with Amyloid-Lowering or Cholinergic α7 Nicotinic Receptor DrugsThe alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen.Neurotrophic and neuroprotective actions of (-)- and (+)-phenserine, candidate drugs for Alzheimer's disease.Cell Therapy From Bench to Bedside Translation in CNS Neurorestoratology Era.IGF-1 promotes Brn-4 expression and neuronal differentiation of neural stem cells via the PI3K/Akt pathwayThe roles of amyloid precursor protein (APP) in neurogenesis: Implications to pathogenesis and therapy of Alzheimer disease.Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans.Denervated hippocampus provides a favorable microenvironment for neuronal differentiation of endogenous neural stem cells.Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately?Targeting aldehyde dehydrogenase: a potential approach for cell labeling.Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis.Alternative splicing modulates stem cell differentiation.Stem cells for the treatment of neurodegenerative diseases.Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications.Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions.Concise review: Can stem cells be used to treat or model Alzheimer's disease?Stem cell applications in regenerative medicine for neurological disorders.New pharmacological approaches to the cholinergic system: an overview on muscarinic receptor ligands and cholinesterase inhibitors.RNA processing-associated molecular mechanisms of neurodegenerative diseases.Neurotrophic factors promote cholinergic differentiation in human embryonic stem cell-derived neurons.MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signalingRepositioning drugs for traumatic brain injury - N-acetyl cysteine and PhenserineNeural stem cell transplantation improves spatial learning and memory via neuronal regeneration in amyloid-β precursor protein/presenilin 1/tau triple transgenic mice.Response of neural precursor cells in the brain of Parkinson's disease mouse model after LIF administration.Effects of Acetylcholine on β-Amyloid-Induced cPLA2 Activation in the TB Neuroectodermal Cell Line: Implications for the Pathogenesis of Alzheimer's Disease.Effects of Brn-4 on the neuronal differentiation of neural stem cells derived from rat midbrain.The effects of aging on Amyloid-β42-induced neurodegeneration and regeneration in adult zebrafish brain.Translational inhibition of APP by Posiphen: Efficacy, pharmacodynamics, and pharmacokinetics in the APP/PS1 mouse.
P2860
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P2860
Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Modulation of human neural ste ...... transgenic mice by phenserine.
@ast
Modulation of human neural ste ...... transgenic mice by phenserine.
@en
type
label
Modulation of human neural ste ...... transgenic mice by phenserine.
@ast
Modulation of human neural ste ...... transgenic mice by phenserine.
@en
prefLabel
Modulation of human neural ste ...... transgenic mice by phenserine.
@ast
Modulation of human neural ste ...... transgenic mice by phenserine.
@en
P2093
P2860
P356
P1476
Modulation of human neural ste ...... transgenic mice by phenserine
@en
P2093
Amelia Marutle
Masao Ohmitsu
Mats Nilbratt
Nigel H Greig
P2860
P304
12506-12511
P356
10.1073/PNAS.0705346104
P407
P577
2007-07-17T00:00:00Z