SUMO modification regulates MafB-driven macrophage differentiation by enabling Myb-dependent transcriptional repression
about
Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiationThe transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activationMafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages.Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by MybSUMOylated MAFB promotes colorectal cancer tumorigenesis.Tissue macrophage identity and self-renewal.Sumoylation regulates the transcriptional activity of MafA in pancreatic beta cells.Regulatory interdependence of myeloid transcription factors revealed by Matrix RNAi analysis.MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis.MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice.Sumoylation in Development and Differentiation.
P2860
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P2860
SUMO modification regulates MafB-driven macrophage differentiation by enabling Myb-dependent transcriptional repression
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
SUMO modification regulates Ma ...... ent transcriptional repression
@ast
SUMO modification regulates Ma ...... ent transcriptional repression
@en
type
label
SUMO modification regulates Ma ...... ent transcriptional repression
@ast
SUMO modification regulates Ma ...... ent transcriptional repression
@en
prefLabel
SUMO modification regulates Ma ...... ent transcriptional repression
@ast
SUMO modification regulates Ma ...... ent transcriptional repression
@en
P2093
P2860
P356
P1476
SUMO modification regulates Ma ...... ent transcriptional repression
@en
P2093
Camille Du Roure
Claas Otto
Ellis Jaffray
Laurent Vanhille
Sandrine Sarrazin
Silke Tillmanns
Youssef Bakri
P2860
P304
P356
10.1128/MCB.01811-06
P407
P577
2007-06-04T00:00:00Z