Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.

Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.

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http://www.wikidata.org/entity/Q35962657
Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein-protein interaction inhibitors.Efficient Binding of the NOS1AP C-Terminus to the nNOS PDZ Pocket Requires the Concerted Action of the PDZ Ligand Motif, the Internal ExF Site and Structural Integrity of an Independent ElementZL006, a small molecule inhibitor of PSD-95/nNOS interaction, does not induce antidepressant-like effects in two genetically predisposed rat models of depression and control animals.Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence.2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor.Regional Specific Modulation of Stress-Induced Neuronal Activation Associated with the PSD95/NOS Interaction Inhibitor ZL006 in the Wistar Kyoto Rat.Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice.Employment of Molecularly Imprinted Polymers to High-Throughput Screen nNOS-PSD-95 Interruptions: Structure and Dynamics Investigations on Monomer-Template Complexation.Small molecule inhibitors of PSD95-nNOS protein-protein interactions suppress formalin-evoked Fos protein expression and nociceptive behavior in rats.ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viabilityPSD95 and nNOS interaction as a novel molecular target to modulate conditioned fear: relevance to PTSD
P2860

Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.

Item
http://www.wikidata.org/entity/Q35962657
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
@ast
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
@en
type
label
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
@ast
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
@en
prefLabel
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
@ast
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
@en
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Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
@en
P2093
P2860
P304
P31
P356
10.1016/J.NEUROPHARM.2015.05.038
P407
P478
P50
P577
P698
P921
P932