Mitochondrial regulation of epigenetics and its role in human diseases. - sprookjes - yvandenbroek - TriplyDB

Mitochondrial regulation of epigenetics and its role in human diseases.

Mitochondrial regulation of epigenetics and its role in human diseases.

http://www.wikidata.org/entity/Q36012679

about

Mitophagy plays a central role in mitochondrial ageing The mitochondrial side of epigenetics Mitochondria and reactive oxygen species: physiology and pathophysiology Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways Mitochondria, endothelial cell function, and vascular diseases.Increased prevalence of malignancy in adult mitochondrial disorders Cancer as a mitochondrial metabolic disease.Placental mitochondrial methylation and exposure to airborne particulate matter in the early life environment: An ENVIRONAGE birth cohort study.Biomarkers of chondriome topology and function: implications for the extension of healthy aging.Increased Histone Deacetylase Activity Involved in the Suppressed Invasion of Cancer Cells Survived from ALA-Mediated Photodynamic Treatment.Impaired mitochondrial metabolism and mammary carcinogenesis CpG methylation patterns of human mitochondrial DNA Mitochondrial content is central to nuclear gene expression: Profound implications for human health.Novel antioxidants protect mitochondria from the effects of oligomeric amyloid beta and contribute to the maintenance of epigenome function.Mitochondria as a target of environmental toxicants.Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.Placental mitochondrial DNA and CYP1A1 gene methylation as molecular signatures for tobacco smoke exposure in pregnant women and the relevance for birth weight.Mitochondrial dysfunction and oxidative stress in aging and cancer.Cancer as a metabolic disease: implications for novel therapeutics.The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related complex disease.Intraclonal recovery of 'slow clones'-a manifestation of genomic instability: are mitochondria the key to an explanation?Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: the pivotal role of mitochondria.Role of mtDNA-related mitoepigenetic phenomena in cancer.From radioresistance to radiosensitivity: In vitro evolution of L5178Y lymphoma.Mitochondrial-epigenetic crosstalk in environmental toxicology.Impacts of the Mitochondrial Genome on the Relationship of Long-Term Ambient Fine Particle Exposure with Blood DNA Methylation Age.HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging.Mitochondrial DNA variants in colorectal carcinogenesis: Drivers or passengers?Mitochondrial determinants of cancer health disparities.Press-pulse: a novel therapeutic strategy for the metabolic management of cancer.Natural selection of mitochondria during somatic lifetime promotes healthy aging.The Landscape of mtDNA Modifications in Cancer: A Tale of Two Cities.Epigenetic modification of miR-663 controls mitochondria-to-nucleus retrograde signaling and tumor progression.Single molecule mtDNA fiber FISH for analyzing numtogenesis.Mitochondrial Genomic Backgrounds Affect Nuclear DNA Methylation and Gene Expression.Lipopolysaccharide markedly changes glucose metabolism and mitochondrial function in the longissimus muscle of pigs.Epigenetic control of variation and stochasticity in metabolic disease.Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts.

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Mitochondrial regulation of epigenetics and its role in human diseases.

http://www.wikidata.org/entity/Q36012679

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Mitochondrial regulation of epigenetics and its role in human diseases.

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Keshav K Singh

http://www.w3.org/2001/XMLSchema#string

Sheroy Minocherhomji

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Trygve O Tollefsbol

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P2860

Ancient mtDNA genetic variants modulate mtDNA transcription and replication

Translating the Histone Code

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

CpG methylation, chromatin structure and gene silencing-a three-way connection.

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter

Mitochondrial DNA replication and disease: insights from DNA polymerase γ mutations

MicroRNA-137 promoter methylation in oral rinses from patients with squamous cell carcinoma of the head and neck is associated with gender and body mass index

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326-334

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10.4161/EPI.19547

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4

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22419065

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