GATA2 is required for lymphatic vessel valve development and maintenance.
about
Heterogeneity in the lymphatic vascular system and its originEPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis.Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valvesLaminar flow downregulates Notch activity to promote lymphatic sprouting.Morphogenesis of the lymphatic vasculature: A focus on new progenitors and cellular mechanisms important for constructing lymphatic vessels.Children's Interstitial and Diffuse Lung Disease. Progress and Future Horizons.RASA1 regulates the function of lymphatic vessel valves in mice.The lymphatic vasculature: development and role in shaping immunity.Lymphatic pumping: mechanics, mechanisms and malfunction.Building the drains: the lymphatic vasculature in health and disease.Lymphatic vessel development: fluid flow and valve-forming cells.microRNAs in the Lymphatic Endothelium: Master Regulators of Lineage Plasticity and Inflammation.Vascular heterogeneity and specialization in development and disease.Heterogeneity of GATA2-related myeloid neoplasms.Intestinal lymphatic vasculature: structure, mechanisms and functions.GATA2 null mutation associated with incomplete penetrance in a family with Emberger syndrome.The Lymphatic System: Integral Roles in Immunity.Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations.Intraluminal valves: development, function and disease.Experimental Models Used to Assess Lymphatic Contractile Function.Hdac3 regulates lymphovenous and lymphatic valve formation.Human venous valve disease caused by mutations in FOXC2 and GJC2.Defective lymphatic valve development and chylothorax in mice with a lymphatic-specific deletion of Connexin43.Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes.KLF2-mediated Disruption of PPARγ Signaling in Lymphatic Endothelial Cells Exposed to Chronically Increased Pulmonary Lymph Flow.
P2860
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P2860
GATA2 is required for lymphatic vessel valve development and maintenance.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
GATA2 is required for lymphatic vessel valve development and maintenance.
@ast
GATA2 is required for lymphatic vessel valve development and maintenance.
@en
type
label
GATA2 is required for lymphatic vessel valve development and maintenance.
@ast
GATA2 is required for lymphatic vessel valve development and maintenance.
@en
prefLabel
GATA2 is required for lymphatic vessel valve development and maintenance.
@ast
GATA2 is required for lymphatic vessel valve development and maintenance.
@en
P2093
P2860
P50
P356
P1476
GATA2 is required for lymphatic vessel valve development and maintenance
@en
P2093
Cansaran Saygili Demir
Christopher N Hahn
David M Lawrence
Drew L Sutton
Genevieve A Secker
Naoyuki Miura
Philippa H Stokes
Sebastien P Tabruyn
Tatiana V Petrova
Yan Agalarov
P2860
P304
P356
10.1172/JCI78888
P407
P50
P577
2015-07-27T00:00:00Z