Conformational properties of the disease-causing Z variant of α1-antitrypsin revealed by theory and experiment.
about
Molecular mechanisms of disease-causing missense mutationsThe shapes of Z-α1-antitrypsin polymers in solution support the C-terminal domain-swap mechanism of polymerization.Reglucosylation by UDP-glucose:glycoprotein glucosyltransferase 1 delays glycoprotein secretion but not degradation.The Z mutation alters the global structural dynamics of α1-antitrypsin.Emerging genetics of COPD.Molecular Mechanism of Z α1-Antitrypsin DeficiencySmoothing a rugged protein folding landscape by sequence-based redesign.An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behaviour.Conformational preludes to the latency transition in PAI-1 as determined by atomistic computer simulations and hydrogen/deuterium-exchange mass spectrometry.Well-Known and Less Well-Known Functions of Alpha-1 Antitrypsin. Its Role in Chronic Obstructive Pulmonary Disease and Other Disease Developments.Dynamic properties of the native free antithrombin from molecular dynamics simulations: computational evidence for solvent- exposed Arg393 side chain.
P2860
Q27021940-7E288B79-FEBE-47B1-A549-4DD6FD278A97Q34424129-3E1A71F4-F472-4FC5-858B-9A1DF842F28EQ35027539-589ECF3B-444B-405B-AD61-DB850032904DQ35236899-1E8DCAD5-34CE-4EE8-89F2-D4DFDCDB6DA6Q36389310-E75A6288-BFF0-4D55-A1D8-D7C70D037EDEQ37117306-058DC828-3D44-46B5-BA04-3298A3C3C0A1Q37282499-7F2AEC5C-8E75-4D1F-832A-EAA3769459DCQ37605015-EA26602B-13AD-4DB2-9D6F-2140F783EF14Q38659159-23E512E4-21EC-4207-ACA2-796144803C20Q51465416-7892220E-9387-4EA4-9287-47FE0342231FQ53160786-DB1BD776-85C0-47D5-994F-988480D8781D
P2860
Conformational properties of the disease-causing Z variant of α1-antitrypsin revealed by theory and experiment.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Conformational properties of t ...... aled by theory and experiment.
@ast
Conformational properties of t ...... aled by theory and experiment.
@en
type
label
Conformational properties of t ...... aled by theory and experiment.
@ast
Conformational properties of t ...... aled by theory and experiment.
@en
prefLabel
Conformational properties of t ...... aled by theory and experiment.
@ast
Conformational properties of t ...... aled by theory and experiment.
@en
P2093
P2860
P1433
P1476
Conformational properties of t ...... aled by theory and experiment.
@en
P2093
Anja S Knaupp
Ashley M Buckle
Itamar Kass
Stephen P Bottomley
P2860
P304
P356
10.1016/J.BPJ.2012.05.023
P407
P577
2012-06-19T00:00:00Z