Mitochondrial energy metabolism in heart failure: a question of balance. - sprookjes - yvandenbroek - TriplyDB

Mitochondrial energy metabolism in heart failure: a question of balance.

Mitochondrial energy metabolism in heart failure: a question of balance.

http://www.wikidata.org/entity/Q36070074

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Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes PGC-1 coactivators: inducible regulators of energy metabolism in health and disease Thioredoxin and ventricular remodeling A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation An experimental approach to study the function of mitochondria in cardiomyopathy Diabetic cardiomyopathy: bench to bedside Transition metals and mitochondrial metabolism in the heart PGC-1 proteins and heart failure Optimization of cardiac metabolism in heart failure PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.A Drosophila model of high sugar diet-induced cardiomyopathy Metabolic shifts during aging and pathology Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery Phosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodeling DIGE proteome analysis reveals suitability of ischemic cardiac in vitro model for studying cellular response to acute ischemia and regeneration Modeling-Enabled Characterization of Novel NLRX1 Ligands Multiphasic triacylglycerol dynamics in the intact heart during acute in vivo overexpression of CD36 A PPARα promoter variant impairs ERR-dependent transactivation and decreases mortality after acute coronary ischemia in patients with diabetes Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.Lrrc10 is required for early heart development and function in zebrafish A 2-D gel reference map of the basic human heart proteome.Altered spatiotemporal dynamics of the mitochondrial membrane potential in the hypertrophied heart.Mitofusin 1 is negatively regulated by microRNA 140 in cardiomyocyte apoptosis.Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway.Astragaloside IV alleviates heart failure via activating PPARα to switch glycolysis to fatty acid β-oxidation.Genome-wide analysis of functional and evolutionary features of tele-enhancers.Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice.Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps.Maintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function.Abnormal mitochondrial L-arginine transport contributes to the pathogenesis of heart failure and rexoygenation injury Metabolic imprinting, programming and epigenetics - a review of present priorities and future opportunities.Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricle.Mitochondrial calcium overload is a key determinant in heart failure.Divergent mitochondrial biogenesis responses in human cardiomyopathy Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.PGC-1 coactivators in the control of energy metabolism.Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.Do mitochondria limit hot fish hearts? Understanding the role of mitochondrial function with heat stress in Notolabrus celidotus.

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P2860

Mitochondrial energy metabolism in heart failure: a question of balance.

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Mitochondrial energy metabolism in heart failure: a question of balance.

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Mitochondrial energy metabolism in heart failure: a question of balance.

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Mitochondrial energy metabolism in heart failure: a question of balance.

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Mitochondrial energy metabolism in heart failure: a question of balance.

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Journal of Clinical Investigation

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Mitochondrial energy metabolism in heart failure: a question of balance.

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Daniel P Kelly

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Janice M Huss

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Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3

The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha

NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency

Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells

Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis

Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

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