Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism
about
Skeletal muscle as a therapeutic target for delaying type 1 diabetic complicationsRegulation of brown adipocyte metabolism by myostatin/follistatin signalingAdaptive thermogenesis in adipocytes: is beige the new brown?Preliminary investigation into a potential role for myostatin and its receptor (ActRIIB) in lean and obese horses and ponies.Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis.Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6Development of novel activin-targeted therapeutics.The adipocyte clock controls brown adipogenesis through the TGF-β and BMP signaling pathwaysNovel Function of Rev-erbα in Promoting Brown AdipogenesisTGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulatorInhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues.Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification.Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle.Increasing muscle mass to improve metabolism.Increased activin bioavailability enhances hepatic insulin sensitivity while inducing hepatic steatosis in male mice.Through thick and thin: a circulating growth factor inhibits age-related cardiac hypertrophy.Increased apoptosis and browning of TAK1-deficient adipocytes protects against obesityAgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy.The function of myostatin in the regulation of fat mass in mammalsA new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasisMolecular pathways regulating the formation of brown-like adipocytes in white adipose tissue.Role of BMP7 in appetite regulation, adipogenesis, and energy expenditure.Activins and Inhibins: Roles in Development, Physiology, and Disease.Brown adipose tissue as a secretory organ.Turning on brown fat and muscle metabolism: hedging your bets.Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues.Bimagrumab improves body composition and insulin sensitivity in insulin-resistant individuals.Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.Modulation of transforming growth factor-β/follistatin signaling and white adipose browning: therapeutic implications for obesity related disorders.Brown and Beige Adipose Tissues in Health and Disease.Assessment of goat activin receptor type IIB knockdown by short hairpin RNAs in vitro.Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of MyostatinBrown Adipose Tissue
P2860
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P2860
Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Blockade of the activin recept ...... chondrial oxidative metabolism
@ast
Blockade of the activin recept ...... chondrial oxidative metabolism
@en
type
label
Blockade of the activin recept ...... chondrial oxidative metabolism
@ast
Blockade of the activin recept ...... chondrial oxidative metabolism
@en
prefLabel
Blockade of the activin recept ...... chondrial oxidative metabolism
@ast
Blockade of the activin recept ...... chondrial oxidative metabolism
@en
P2093
P2860
P921
P356
P1476
Blockade of the activin recept ...... chondrial oxidative metabolism
@en
P2093
Anne-Ulrike Trendelenburg
Ben Murray
Brian Richardson
Brigitte Fournier
David J Glass
David Marcellin
Eliane Pierrel
Elke Persohn
Estelle Lach-Trifilieff
Florian Bombard
P2860
P304
P356
10.1128/MCB.06575-11
P407
P577
2012-05-14T00:00:00Z