Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
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MiRNAs and miRNA Polymorphisms Modify Drug ResponseCYP2C9 genotype vs. metabolic phenotype for individual drug dosing--a correlation analysis using flurbiprofen as probe drugRegulation of human CYP2C9 expression by electrophilic stress involves activator protein 1 activation and DNA looping.Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancerMed25 is required for estrogen receptor alpha (ERα)-mediated regulation of human CYP2C9 expression.Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosisHypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex.Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19.CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver.MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyThe independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and the metabolism of atorvastatin.Incubation of whole blood at room temperature does not alter the plasma concentrations of microRNA-16 and -223.Identification of hub genes and pathways associated with hepatocellular carcinoma based on network strategy.Systematic tracking of disrupted modules identifies significant genes and pathways in hepatocellular carcinoma.Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107.Role of microRNAs in the regulation of drug metabolism and disposition genes in diabetes and liver disease.Role of miR-107 and its signaling pathways in diseases.MicroRNAs as key regulators of xenobiotic biotransformation and drug response.Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines.MicroRNA hsa-miR-29a-3p modulates CYP2C19 in human liver cells.Hsa-miR-27a is involved in the regulation of CYP3A4 expression in human livers from Chinese Han population.Peroxisome Proliferator-Activated Receptor α Activation Suppresses Cytochrome P450 Induction Potential in Mice Treated with Gemfibrozil.Pharmacoepigenetics: an element of personalized therapy?Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.Upregulation of human CYP2C9 expression by Bisphenol A via estrogen receptor alpha (ERα) and Med25.Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR.Pharmacogenomic Impact of CYP2C19 Variation on Clopidogrel Therapy in Precision Cardiovascular Medicine.Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation.The down-regulation of the CYP2C19 gene is associated with aggressive tumor potential and the poorer recurrence-free survival of hepatocellular carcinoma.The implications of signaling lipids in cancer metastasisNovel Roles of Non-Coding RNAs in Opioid Signaling and Cardioprotection
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P2860
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
@ast
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
@en
type
label
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
@ast
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
@en
prefLabel
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
@ast
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
@en
P2093
P2860
P356
P1476
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
@en
P2093
Joyce A Goldstein
Sailesh Surapureddi
Sherry Coulter
Shu-Yun Zhang
Stephen S Ferguson
P2860
P304
P356
10.1124/MOL.112.078386
P577
2012-06-20T00:00:00Z