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The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1)Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome.GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival.Direct binding of the Kex2p cytosolic tail to the VHS domain of yeast Gga2p facilitates TGN to prevacuolar compartment transport and is regulated by phosphorylationEndocytosis as a mode to regulate functional expression of two-pore domain potassium (K₂p) channels.Cargo trafficking from the trans-Golgi network towards the endosome.RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Do GGA adaptors bind internal DXXLL motifs?
@ast
Do GGA adaptors bind internal DXXLL motifs?
@en
type
label
Do GGA adaptors bind internal DXXLL motifs?
@ast
Do GGA adaptors bind internal DXXLL motifs?
@en
prefLabel
Do GGA adaptors bind internal DXXLL motifs?
@ast
Do GGA adaptors bind internal DXXLL motifs?
@en
P2093
P2860
P1433
P1476
Do GGA adaptors bind internal DXXLL motifs?
@en
P2093
Balraj Doray
Stuart Kornfeld
Tom J Brett
P2860
P304
P356
10.1111/J.1600-0854.2012.01396.X
P50
P577
2012-07-24T00:00:00Z