Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression.
about
HACE1 Negatively Regulates Virus-Triggered Type I IFN Signaling by Impeding the Formation of the MAVS-TRAF3 Complex.Common variations within HACE1 gene and neuroblastoma susceptibility in a Southern Chinese population.The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitriesTranslational Research and Plasma Proteomic in Cancer.The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma.Rho GTPases, their post-translational modifications, disease-associated mutations and pharmacological inhibitors.New Aspects on Bacterial Effectors Targeting Rho GTPases.Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.Association Between HACE1 Gene Polymorphisms and Wilms' Tumor Risk in a Chinese Population.Protein kinase C δ-dependent regulation of Ubiquitin-proteasome system function in breast cancer.The role of ubiquitination and deubiquitination in the regulation of cell junctions.The Rac GTPase in Cancer: From Old Concepts to New Paradigms.Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.Pirh2 mediates the sensitivity of myeloma cells to bortezomib via canonical NF-κB signaling pathway.Overexpression of HACE1 in gastric cancer inhibits tumor aggressiveness by impeding cell proliferation and migration.
P2860
Q36947062-FAAE90C8-B2ED-41E8-ABD0-2EB20291D5BDQ37641476-3FD1031E-1230-4FA6-B98B-30BC65B1FB03Q37710032-D8998E62-7056-4B25-B971-91C866B87EB6Q38610869-FF309000-AE9A-4945-B9B7-7347DB9260B1Q38788923-E0FD9B80-2E74-45B0-B396-3CB14E24AEE7Q38933808-057CD0ED-93EE-4619-A961-CD71BDB13A6AQ38981722-E4C3C8B6-CA26-40EA-BA87-8EBF9B862FC1Q42315389-ED6A6D5C-5B39-4165-87B5-CF6596C120ABQ47290680-316D3146-B3B9-40C1-831F-130C7BC5C325Q47567147-74876EEE-15A3-4C19-A05B-BFA678416565Q47592089-87ACE6D1-2C0F-45E4-B5D8-6DF746D755FEQ47953335-ABD3B256-FD96-4046-926C-84DB5DFF2663Q49538387-401FB3D4-A815-4091-AAB0-865D17B8E35DQ50020971-D0EFBFE9-D4A8-429C-AB4F-D4915D5A73A3Q55324989-6E8CCE26-846D-437B-BC9F-A28605189195
P2860
Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Loss of the E3 ubiquitin ligas ...... to breast cancer progression.
@ast
Loss of the E3 ubiquitin ligas ...... to breast cancer progression.
@en
type
label
Loss of the E3 ubiquitin ligas ...... to breast cancer progression.
@ast
Loss of the E3 ubiquitin ligas ...... to breast cancer progression.
@en
prefLabel
Loss of the E3 ubiquitin ligas ...... to breast cancer progression.
@ast
Loss of the E3 ubiquitin ligas ...... to breast cancer progression.
@en
P2860
P356
P1433
P1476
Loss of the E3 ubiquitin ligas ...... to breast cancer progression.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2014.468
P407
P577
2015-02-09T00:00:00Z