The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel - sprookjes - yvandenbroek - TriplyDB

The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel

The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel

http://www.wikidata.org/entity/Q36289190

about

SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells.Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancer.miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies Suppression of annexin A11 in ovarian cancer: implications in chemoresistance.Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.ProbFAST: Probabilistic functional analysis system tool.Loss of PFKFB4 induces cell death in mitotically arrested ovarian cancer cells Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response.RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells.Limitations in Adjuvant Breast Cancer Therapy: The Predictive Potential of Pharmacogenetics and Pharmacogenomics.Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.The role of TGFBI in mesothelioma and breast cancer: association with tumor suppression.Systems analysis of a mouse xenograft model reveals annexin A1 as a regulator of gene expression in tumor stroma.Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression.MicroRNA-mediated regulation of extracellular matrix formation modulates somatic cell reprogramming MiR-21 plays an important role in radiation induced carcinogenesis in BALB/c mice by directly targeting the tumor suppressor gene Big-h3.Gallotannin imposes S phase arrest in breast cancer cells and suppresses the growth of triple-negative tumors in vivo.TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cells.Src family kinases and paclitaxel sensitivity.A genistein derivative, ITB-301, induces microtubule depolymerization and mitotic arrest in multidrug-resistant ovarian cancer.Lysosomal trafficking of TGFBIp via caveolae-mediated endocytosis.Up-regulation of miR-877 induced by paclitaxel inhibits hepatocellular carcinoma cell proliferation though targeting FOXM1.Proteomic identification of betaig-h3 as a lysophosphatidic acid-induced secreted protein of human mesenchymal stem cells: paracrine activation of A549 lung adenocarcinoma cells by betaig-h3.TGFBI promoter hypermethylation correlating with paclitaxel chemoresistance in ovarian cancer.Bioinformatics Analyses of the Role of Vascular Endothelial Growth Factor in Patients with Non-Small Cell Lung Cancer Reversal of Chemoresistance in Ovarian Cancer by Co-Delivery of a P-Glycoprotein Inhibitor and Paclitaxel in a Liposomal Platform.SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells.Transforming growth Factor-Beta-Induced Protein (TGFBI)/(βig-H3): a matrix protein with dual functions in ovarian cancer.ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells.Release of TGFβig-h3 by gastric myofibroblasts slows tumor growth and is decreased with cancer progression.Expression and correlation of Lewis y antigen and TGF-β1 in ovarian epithelial carcinoma.Identification of heterogeneity among soft tissue sarcomas by gene expression profiles from different tumors Tubulin-targeting agent combination therapies: dosing schedule could matter.Altered protein conformation and lower stability of the dystrophic transforming growth factor beta-induced protein mutants.Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints.Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel

P2860

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P2860

The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel

http://www.wikidata.org/entity/Q36289190

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

The extracellular matrix prote ...... ovarian cancers to paclitaxel

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The extracellular matrix prote ...... ovarian cancers to paclitaxel

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type

label

The extracellular matrix prote ...... ovarian cancers to paclitaxel

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The extracellular matrix prote ...... ovarian cancers to paclitaxel

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prefLabel

The extracellular matrix prote ...... ovarian cancers to paclitaxel

@ast

The extracellular matrix prote ...... ovarian cancers to paclitaxel

@en

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J.CCR.2007.11.014

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P1476

The extracellular matrix prote ...... ovarian cancers to paclitaxel

@en

P2093

Adam McGeoch

http://www.w3.org/2001/XMLSchema#string

Ahmed Ashour Ahmed

http://www.w3.org/2001/XMLSchema#string

Anthony D Mills

http://www.w3.org/2001/XMLSchema#string

Ashraf E K Ibrahim

http://www.w3.org/2001/XMLSchema#string

Barbara Nicke

http://www.w3.org/2001/XMLSchema#string

Jillian Temple

http://www.w3.org/2001/XMLSchema#string

Maria Vias

http://www.w3.org/2001/XMLSchema#string

Robin Crawford

http://www.w3.org/2001/XMLSchema#string

Ronald A Laskey

http://www.w3.org/2001/XMLSchema#string

P2860

TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line

cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol.

Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples

Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

How cells get the right chromosomes

Focal adhesion kinase, Rap1, and transcriptional induction of vascular endothelial growth factor.

Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics.

A gene-expression signature to predict survival in breast cancer across independent data sets.

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514-527

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scholarly article

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10.1016/J.CCR.2007.11.014

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6

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12

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Charles Swanton

James D Brenton

Charlie E Massie

Stephen D. Bell

Cherie Blenkiron

N Gopalakrishna Iyer

Julian Downward

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2007-12-01T00:00:00Z

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5778980

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18068629

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extracellular matrix

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2148463

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