Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.
about
The sense of smell, its signalling pathways, and the dichotomy of cilia and microvilli in olfactory sensory cellsEpithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airwaysRegulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9)Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial culturesAirway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing miceTransgenic hCFTR expression fails to correct β-ENaC mouse lung diseaseSPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavageEpithelial Anion Transport as Modulator of Chemokine SignalingMucociliary dysfunction in HIV and smoked substance abuseEpithelial Na(+) channel regulation by cytoplasmic and extracellular factorsMicroscale imaging of cilia-driven fluid flowMolecular basis for pH-dependent mucosal dehydration in cystic fibrosis airwaysActivation of the epithelial sodium channel (ENaC) by the alkaline protease from Pseudomonas aeruginosaCFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epitheliumNon-invasive airway health assessment: synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo.Model demonstrates functional purpose of the nasal cycle.Smoking is associated with shortened airway ciliaENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.Effects of secretagogues on net and unidirectional liquid fluxes across porcine bronchial airways.Sodium tanshinone IIA sulfonate stimulated Cl- secretion in mouse trachea.New horizons in the treatment of cystic fibrosis.Purinergic receptors in airway epithelia.The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel.Defining an inhibitory domain in the gamma subunit of the epithelial sodium channelHuman alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling.Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.Biomarkers of Exposure to New and Emerging Tobacco and Nicotine Delivery Products.Experimental human pneumococcal carriage augments IL-17A-dependent T-cell defence of the lung.Nasal potential difference to detect Na+ channel dysfunction in acute lung injury.CFTR and lung homeostasis.Domiciliary humidification improves lung mucociliary clearance in patients with bronchiectasis.Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibitionFunctional apical large conductance, Ca2+-activated, and voltage-dependent K+ channels are required for maintenance of airway surface liquid volume.Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching.Mucous solids and liquid secretion by airways: studies with normal pig, cystic fibrosis human, and non-cystic fibrosis human bronchi.Modulation of the epithelial sodium channel (ENaC) by bacterial metalloproteases and protease inhibitors.Measurement of the airway surface liquid volume with simple light refraction microscopy.Infection by Toxoplasma gondii, a severe parasite in neonates and AIDS patients, causes impaired anion secretion in airway epithelia.Characteristics of chloride transport in nasal mucosa from patients with primary ciliary dyskinesia.Cigarette smoke exposure reveals a novel role for the MEK/ERK1/2 MAPK pathway in regulation of CFTR
P2860
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P2860
Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Soluble mediators, not cilia, ...... superficial airway epithelia.
@ast
Soluble mediators, not cilia, ...... superficial airway epithelia.
@en
type
label
Soluble mediators, not cilia, ...... superficial airway epithelia.
@ast
Soluble mediators, not cilia, ...... superficial airway epithelia.
@en
prefLabel
Soluble mediators, not cilia, ...... superficial airway epithelia.
@ast
Soluble mediators, not cilia, ...... superficial airway epithelia.
@en
P2093
P2860
P356
P1476
Soluble mediators, not cilia, ...... superficial airway epithelia.
@en
P2093
Laura Trout
Richard C Boucher
Robert Tarran
Scott H Donaldson
P2860
P304
P356
10.1085/JGP.200509468
P577
2006-05-01T00:00:00Z