Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
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Human Ribonuclease H1 resolves R loops and thereby enables progression of the DNA replication fork.The Role of Replication-Associated Repair Factors on R-LoopsThe Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage.A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation.Alternative mRNA processing sites decrease genetic variability while increasing functional diversity.Replication stress induces accumulation of FANCD2 at central region of large fragile genes.Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops.Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability.RNase H1 Cooperates with DNA Gyrases to Restrict R-Loops and Maintain Genome Integrity in Arabidopsis Chloroplasts.Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids.TRF1 participates in chromosome end protection by averting TRF2-dependent telomeric R loops.The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations.Cytosolic Genomic DNA functions as a Natural Antisense.ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSBHuman proteins that interact with RNA/DNA hybrids
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P2860
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年學術文章
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2017年學術文章
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2017年學術文章
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name
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
@ast
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
@en
type
label
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
@ast
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
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prefLabel
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
@ast
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
@en
P2093
P2860
P1433
P1476
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
@en
P2093
Hai Dang Nguyen
Sumanprava Giri
Timothy A Graubert
P2860
P304
832-847.e4
P356
10.1016/J.MOLCEL.2017.01.029
P577
2017-03-01T00:00:00Z