An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
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Phenotypic diversity of breast cancer-related mutations in metalloproteinase-disintegrin ADAM12A disintegrin and metalloproteinase-12 (ADAM12): function, roles in disease progression, and clinical implicationsAlternative mRNA splicing generates two distinct ADAM12 prodomain variants.ADAM12-L is a direct target of the miR-29 and miR-200 families in breast cancer.The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.Metalloproteinase-disintegrin ADAM12 is associated with a breast tumor-initiating cell phenotype.Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancerTherapeutic targets in triple negative breast cancer.ADAM12 is a prognostic factor associated with an aggressive molecular subtype of high-grade serous ovarian carcinoma.Metalloprotease-dependent activation of EGFR modulates CD44+/CD24- populations in triple negative breast cancer cells through the MEK/ERK pathway.EGFR conjunct FSCN1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer.ADAM12 Is a Novel Regulator of Tumor Angiogenesis via STAT3 Signaling.Proteomic screening identifies the zonula occludens protein ZO-1 as a new partner for ADAM12 in invadopodia-like structures.
P2860
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P2860
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
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2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
@ast
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
@en
type
label
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
@ast
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
@en
prefLabel
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
@ast
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
@en
P2093
P2860
P1476
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
@en
P2093
Anna Zolkiewska
Fariba Behbod
Sara Duhachek-Muggy
P2860
P2888
P304
P356
10.1007/S10549-012-2220-4
P407
P50
P577
2012-08-29T00:00:00Z