Cyclase-associated protein (CAP) acts directly on F-actin to accelerate cofilin-mediated actin severing across the range of physiological pH.
about
Coronin Enhances Actin Filament Severing by Recruiting Cofilin to Filament Sides and Altering F-Actin ConformationAip1 destabilizes cofilin-saturated actin filaments by severing and accelerating monomer dissociation from ends.Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin.High-speed depolymerization at actin filament ends jointly catalysed by Twinfilin and Srv2/CAP.Autonomous and in trans functions for the two halves of Srv2/CAP in promoting actin turnover.Single-molecule imaging of a three-component ordered actin disassembly mechanism.ATP-dependent regulation of actin monomer-filament equilibrium by cyclase-associated protein and ADF/cofilinStructure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics.Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin.Actin and endocytosis in budding yeast.Actin-interacting Protein 1 Promotes Disassembly of Actin-depolymerizing Factor/Cofilin-bound Actin Filaments in a pH-dependent Manner.TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover.The role of cyclase-associated protein in regulating actin filament dynamics - more than a monomer-sequestration factor.ADF/cofilin is not essential but is critically important for actin activities during phagocytosis in Tetrahymena thermophila.Actin network disassembly powers dissemination of Listeria monocytogenes.Functions of cofilin in cell locomotion and invasion.Actin dynamics and cofilin-actin rods in alzheimer disease.The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.Global treadmilling coordinates actin turnover and controls the size of actin networks.Combinatorial genetic analysis of a network of actin disassembly-promoting factors.Mechanisms of actin disassembly.GMF promotes leading-edge dynamics and collective cell migration in vivo.Mammalian and malaria parasite cyclase-associated proteins catalyze nucleotide exchange on G-actin through a conserved mechanism.The C-terminal dimerization motif of cyclase-associated protein is essential for actin monomer regulation.Cadmium favors F-actin depolymerization in rat renal mesangial cells by site-specific, disulfide-based dimerization of the CAP1 protein.Conserved hydrophobic residues in the CARP/β-sheet domain of cyclase-associated protein are involved in actin monomer regulation.Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells.Cyclase-Associated Protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase.Self-incompatibility-induced programmed cell death in field poppy pollen involves dramatic acidification of the incompatible pollen tube cytosol.Structural basis of actin monomer re-charging by cyclase-associated protein.
P2860
Q27309690-2A8A48EC-C96C-412E-9855-D6D4F2CA8DAAQ27316864-9E04C999-ABD8-4CA5-B694-30C806B12754Q27932975-B3F44960-3990-42C6-8CF0-D3E6794CE985Q27935278-8FBC49ED-B231-49A5-BD13-AA4D87AD1CD5Q30650714-2B4BBAC8-1D62-490C-ACD8-2E3155843AACQ30651672-A0A4334F-EB87-42A8-BC25-C1AA6CE00283Q33861326-F08A525D-0B16-4EF8-B63E-CCFA691AADB8Q34431087-56B07479-947B-436A-98B7-4E60084E9B58Q34589289-999A22F1-9814-4F09-884D-4CEA1D2F85B2Q34667847-98BAD3D7-0E96-421B-B9F2-BD72AED8F8FEQ36650336-CC2A3FB6-6C82-4F69-8FD8-5648EC33785AQ36808620-107B6DB3-7DF0-4315-83EB-79864804AEA4Q37061517-35F00F32-5780-492D-B059-9E8257FE027FQ37124797-2340F78F-DCA1-4A93-BC42-7E373DCF5296Q37418474-950E4CAB-C371-49A4-AB26-D4B0D0ED32ABQ38115453-1727EAFD-923C-41E6-BDF8-5DAFF85652C8Q38731927-C13686D1-EF43-4955-A393-3945E571D43CQ39004068-E10FCD53-5361-4D5C-9DF0-6584A4610FACQ39156166-D86F05F1-3424-4937-B74B-8320AFF05C4AQ40765431-E384300F-D853-4647-ABC0-7DF04E36AA5EQ41769939-B08F8422-F255-4E49-AD11-F537426ED1D5Q41932550-3337046F-D2EA-4087-81E4-8675CC3693F4Q42703528-DF3455B8-DB0F-4C1E-B952-839AA99B8D05Q45846114-372287D2-2B0B-45E3-A85F-C7D18C494D8DQ46244845-3221579A-890E-47DF-B7EE-8C9DDE28C283Q48145046-7A92CE86-1427-4C4F-AA5B-927F770CCBC5Q51041186-E3EDBDB7-2A60-45F5-80C1-0525B063D11BQ52331924-811FDBDE-3768-4863-8DC1-A7B6B8ADD272Q53633212-B755015B-2F70-4A17-9F54-28200A79F823Q54986487-1EA0F00C-6122-461E-970A-44AEDD7C86B9
P2860
Cyclase-associated protein (CAP) acts directly on F-actin to accelerate cofilin-mediated actin severing across the range of physiological pH.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Cyclase-associated protein (CA ...... the range of physiological pH.
@ast
Cyclase-associated protein (CA ...... the range of physiological pH.
@en
type
label
Cyclase-associated protein (CA ...... the range of physiological pH.
@ast
Cyclase-associated protein (CA ...... the range of physiological pH.
@en
prefLabel
Cyclase-associated protein (CA ...... the range of physiological pH.
@ast
Cyclase-associated protein (CA ...... the range of physiological pH.
@en
P2860
P356
P1476
Cyclase-associated protein (CA ...... the range of physiological pH.
@en
P2093
Kieran P M Normoyle
William M Brieher
P2860
P304
35722-35732
P356
10.1074/JBC.M112.396051
P407
P577
2012-08-17T00:00:00Z