ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3. - sprookjes - yvandenbroek - TriplyDB

ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3.

ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3.

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Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK)Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth Diminished CRE-Induced Plasticity is Linked to Memory Deficits in Familial Alzheimer's Disease Mice Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation Cocaine potentiates astrocyte toxicity mediated by human immunodeficiency virus (HIV-1) protein gp120 A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition.Neurodevelopmental effects of insulin-like growth factor signaling.Resilience to audiogenic seizures is associated with p-ERK1/2 dephosphorylation in the subiculum of Fmr1 knockout mice.Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity.N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways.Neuronal necrosis is regulated by a conserved chromatin-modifying cascade.U0126 protects cells against oxidative stress independent of its function as a MEK inhibitor.Intrauterine growth restriction affects hippocampal dual specificity phosphatase 5 gene expression and epigenetic characteristics Cdk5 Modulation of mitogen-activated protein kinase signaling regulates neuronal survival.Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats Upregulated Ras/Raf/ERK1/2 signaling pathway: a new hope in the repair of spinal cord injury.Regulation of ERK Kinase by MEK1 Kinase Inhibition in the Brain Emerging role for ERK as a key regulator of neuronal apoptosis.Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging.Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons.PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance.Aggravation of inflammatory response by costimulation with titanium particles and mechanical perturbations in osteoblast- and macrophage-like cells.IGF-1 protects dopamine neurons against oxidative stress: association with changes in phosphokinases.Targeting V1A-vasopressin receptors with [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) identifies a strategy to develop novel anti-cancer therapies.PTEN-mediated ERK1/2 inhibition and paradoxical cellular proliferation following Pnck overexpression.Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progression Activation of stress kinases in the brain of mucopolysaccharidosis IIIB mice.Effects of bee venom on glutamate-induced toxicity in neuronal and glial cells.Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.Effect of alteration of caveolin-1 expression on doxorubicin-induced apoptosis in H9c2 cardiac cells.Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells.Characterizing the "POAGome": A bioinformatics-driven approach to primary open-angle glaucoma.Altered apoptotic responses in neurons lacking RhoB GTPase.Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2.Luteolin protects against reactive oxygen species-mediated cell death induced by zinc toxicity via the PI3K-Akt-NF-κB-ERK-dependent pathway.Oligomer procyanidins from grape seeds induce a paraptosis-like programmed cell death in human glioblastoma U-87 cells.Beneficial Effect of Astragaloside on Alzheimer's Disease Condition Using Cultured Primary Cortical Cells Under β-amyloid Exposure.Ca-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells.

P2860

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P2860

ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3.

http://www.wikidata.org/entity/Q36322105

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

ERK activation promotes neuron ...... nd independently of caspase-3.

@ast

ERK activation promotes neuron ...... nd independently of caspase-3.

@en

type

label

ERK activation promotes neuron ...... nd independently of caspase-3.

@ast

ERK activation promotes neuron ...... nd independently of caspase-3.

@en

prefLabel

ERK activation promotes neuron ...... nd independently of caspase-3.

@ast

ERK activation promotes neuron ...... nd independently of caspase-3.

@en

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ERK activation promotes neuron ...... nd independently of caspase-3.

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P2093

Christine Laliberté

http://www.w3.org/2001/XMLSchema#string

David R Kaplan

http://www.w3.org/2001/XMLSchema#string

Jens Strelau

http://www.w3.org/2001/XMLSchema#string

Klaus Unsicker

http://www.w3.org/2001/XMLSchema#string

Oliver von Bohlen Und Halbach

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Srinivasa Subramaniam

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Ute Zirrgiebel

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P2860

An alternative, nonapoptotic form of programmed cell death

Apoptosis, oncosis, and necrosis. An overview of cell death

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice

A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

The biochemistry of apoptosis

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

The mitogen-activated protein kinase signal transduction pathway

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357-369

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10.1083/JCB.200403028

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165

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8581312

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15123736

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2172179

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