Engineering the processive run length of the kinesin motor
about
Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitroTPX2 Inhibits Eg5 by Interactions with Both Motor and Microtubule.The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load.Diffusion of myosin V on microtubules: a fine-tuned interaction for which E-hooks are dispensableEngineered kinesin motor proteins amenable to small-molecule inhibitionThe myosin X motor is optimized for movement on actin bundles.Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin-microtubule interface.Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules.Analysis of heterodimer formation by Xklp3A/B, a newly cloned kinesin-II from Xenopus laevis.Unusual properties of the fungal conventional kinesin neck domain from Neurospora crassa.Optimal cytoplasmic transport in viral infectionsMonte Carlo analysis of neck linker extension in kinesin molecular motorsModulation of kinesin binding by the C-termini of tubulin.Nucleotide-induced conformations in the neck region of dimeric kinesin.FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry.Optical traps to study properties of molecular motors.Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.The E-hook of tubulin interacts with kinesin's head to increase processivity and speed.Processive movement of single kinesins on crowded microtubules visualized using quantum dots.Dielectric measurement of individual microtubules using the electroorientation method.The distance that kinesin-1 holds its cargo from the microtubule surface measured by fluorescence interference contrast microscopy.Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin.The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation.Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3Transport of beads by several kinesin motorsMyosin V and Kinesin act as tethers to enhance each others' processivity.XMAP215 is a processive microtubule polymerase.Coordination of Kinesin motors pulling on fluid membranes.Processive kinesins require loose mechanical coupling for efficient collective motilityCatalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK.Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.A method for multiprotein assembly in cells reveals independent action of kinesins in complexA flipped ion pair at the dynein-microtubule interface is critical for dynein motility and ATPase activationDirect observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules.Kinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular MachinesPolyglutamylation: a fine-regulator of protein function? 'Protein Modifications: beyond the usual suspects' review series.Flexibility of the neck domain enhances Kinesin-1 motility under load.Insights into the Mechanical Properties of the Kinesin Neck Linker Domain from Sequence Analysis and Molecular Dynamics SimulationsDissection of kinesin's processivity.Novel ways to determine kinesin-1's run length and randomness using fluorescence microscopy.
P2860
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P2860
Engineering the processive run length of the kinesin motor
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Engineering the processive run length of the kinesin motor
@ast
Engineering the processive run length of the kinesin motor
@en
type
label
Engineering the processive run length of the kinesin motor
@ast
Engineering the processive run length of the kinesin motor
@en
prefLabel
Engineering the processive run length of the kinesin motor
@ast
Engineering the processive run length of the kinesin motor
@en
P2093
P2860
P356
P1476
Engineering the processive run length of the kinesin motor
@en
P2093
P2860
P304
P356
10.1083/JCB.151.5.1093
P407
P577
2000-11-01T00:00:00Z