Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine - sprookjes - yvandenbroek - TriplyDB

Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

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Insights into the role of the intestinal microbiota in colon cancer Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium.NADPH oxidase-1 deficiency offers little protection in Salmonella typhimurium-induced typhlitis in mice ROS in gastrointestinal inflammation: Rescue Or Sabotage?A novel fine tuning scheme of miR-200c in modulating lung cell redox homeostasis.Pathobiology of neutrophil-epithelial interactions.Pathogen control at the intestinal mucosa - H2O2 to the rescue.Inhibition of corticotropin-releasing hormone receptor 1 and activation of receptor 2 protect against colonic injury and promote epithelium repair.Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration.The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine.NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice.Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans.Analysis of the Human Mucosal Response to Cholera Reveals Sustained Activation of Innate Immune Signaling Pathways.DUAL OXIDASE: A NOVEL THERAPEUTIC TARGET IN ALLERGIC DISEASE.Chemotaxis allows bacteria to overcome host-generated reactive oxygen species that constrain gland colonization.Hydrogen peroxide production by lactobacilli promotes epithelial restitution during colitis.Increased risk for inflammatory bowel disease in congenital hypothyroidism supports the existence of a shared susceptibility factor.: A Novel Invertebrate Model to Distinguish Intestinal Symbionts From Pathobionts Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease

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Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

http://www.wikidata.org/entity/Q36328418

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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Increased Expression of DUOX2 ...... Homeostasis in Mouse Intestine

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Increased Expression of DUOX2 ...... Homeostasis in Mouse Intestine

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Increased Expression of DUOX2 ...... Homeostasis in Mouse Intestine

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Increased Expression of DUOX2 ...... Homeostasis in Mouse Intestine

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Increased Expression of DUOX2 ...... Homeostasis in Mouse Intestine

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Increased Expression of DUOX2 ...... Homeostasis in Mouse Intestine

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J.GASTRO.2015.07.062

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Gastroenterology

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Increased Expression of DUOX2 ...... Homeostasis in Mouse Intestine

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Andrew B Shreiner

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Chung Owyang

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Helmut Grasberger

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Hiroko Nagao-Kitamoto

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John Y Kao

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Juanita L Merchant

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Kathryn A Eaton

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Min Zhang

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Mohamad El-Zaatari

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Sho Kitamoto

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P2860

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Induction of intestinal Th17 cells by segmented filamentous bacteria

Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

A direct role for dual oxidase in Drosophila gut immunity

Dual oxidase2 is expressed all along the digestive tract

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1849-1859

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Nobuhiko Kamada

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2015-08-07T00:00:00Z

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281815273

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